LOCUS SIU00874.1 158 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 cell redox homeostasis protein. ACCESSION LT708304-2288 PROTEIN_ID SIU00874.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2263C" /note="Mb2263c, -, len: 158 aa. Equivalent to Rv2239c, len: 158 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 158 aa overlap). Conserved hypothetical protein, similar to conserved hypothetical proteins from Mycobacterium leprae (ML1649, 140 aa) and Streptomyces coelicolor A3(2) (SCC8A.28c, 159 aa). Equivalent to ML1649 conserved hypothetical protein (140 aa). FASTA scores: ML1649 conserved hypothetical protein (140 aa) opt: 846, E(): 6.5e-45; 86.429% identity in 140 aa overlap (tr|O69479|O69479 HYPOTHETICAL 15.2 KDA PROTEIN (140 aa); and opt: 447, E(): 1.2e-21; 50.355% identity (51.825% ungapped) in 141 aa overlap. Similarity with ML1649 suggests alternative start at 251198. Protein product from Mb2263c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2263c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="InterPro:IPR021412" /db_xref="UniProtKB/Swiss-Prot:P64960" BEGIN 1 MPIATVCTWP AETEGGSTVV AADHASNYAR KLGIQRDQLI QEWGWDEDTD DDIRAAIEEA 61 CGGELLDEDT DEVIDVVLLW WRDGDGDLVD TLMDAIGPLA EDGVIWVVTP KTGQPGHVLP 121 AEIAEAAPTA GLMPTSSVNL GNWSASRLVQ PKSRAGKR //