LOCUS       SIU00874.1               158 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 cell
            redox homeostasis protein.
ACCESSION   LT708304-2288
PROTEIN_ID  SIU00874.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2263C"
                     /note="Mb2263c, -, len: 158 aa. Equivalent to Rv2239c,
                     len: 158 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 158 aa overlap). Conserved
                     hypothetical protein, similar to conserved hypothetical
                     proteins from Mycobacterium leprae (ML1649, 140 aa) and
                     Streptomyces coelicolor A3(2) (SCC8A.28c, 159 aa).
                     Equivalent to ML1649 conserved hypothetical protein (140
                     aa). FASTA scores: ML1649 conserved hypothetical protein
                     (140 aa) opt: 846, E(): 6.5e-45; 86.429% identity in 140
                     aa overlap (tr|O69479|O69479 HYPOTHETICAL 15.2 KDA PROTEIN
                     (140 aa); and opt: 447, E(): 1.2e-21; 50.355% identity
                     (51.825% ungapped) in 141 aa overlap. Similarity with
                     ML1649 suggests alternative start at 251198. Protein
                     product from Mb2263c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb2263c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="InterPro:IPR021412"
                     /db_xref="UniProtKB/Swiss-Prot:P64960"
BEGIN
        1 MPIATVCTWP AETEGGSTVV AADHASNYAR KLGIQRDQLI QEWGWDEDTD DDIRAAIEEA
       61 CGGELLDEDT DEVIDVVLLW WRDGDGDLVD TLMDAIGPLA EDGVIWVVTP KTGQPGHVLP
      121 AEIAEAAPTA GLMPTSSVNL GNWSASRLVQ PKSRAGKR
//