LOCUS SIU00860.1 124 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 conserved hypothetical protein [SECOND PART] protein. ACCESSION LT708304-2274 PROTEIN_ID SIU00860.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2252" /note="Mb2252, -, len: 124 aa. Equivalent to 3' end of Rv2227, len: 233 aa, from Mycobacterium tuberculosis strain H37Rv, (99.2% identity in 124 aa overlap). Conserved hypothetical protein, similar to conserved hypothetical proteins from various bacteria e.g. gb|AAK22693.1| (AE005746) conserved hypothetical protein from Caulobacter crescentus (234 aa) Smith-Waterman score = 109 bits (429), Expect = 1e-41 Identities = 83/167 (49%). REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, Rv2227 exists as a single gene. In Mycobacterium bovis, a frameshift due to a 1 bp to 2 bp substitution (t-cc) splits Rv2227 in two parts, Mb2251 and Mb2252." /db_xref="InterPro:IPR018655" /db_xref="UniProtKB/TrEMBL:A0A1R3Y0M4" BEGIN 1 MASCHAAGQT RSTALMLKYG TNDWNALHQD LYGELVFPLQ VVINLSDPET DYTGGEFLLV 61 EQRPRAQSRG TAMQLPQGHG YVLTTRDRPV RTSRGWSASP VRHGLSTIRS GERYAMGLIF 121 HDAA //