LOCUS       SIU00851.1               140 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 probable
            conserved membrane protein protein.
ACCESSION   LT708304-2265
PROTEIN_ID  SIU00851.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2243C"
                     /note="Mb2243c, -, len: 140 aa. Equivalent to Rv2219A,
                     len: 140 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 140 aa overlap). Probable membrane
                     protein, similar to SC3H12.05c|AL355740_5 possible
                     integral membrane protein from Streptomyces coelicolor
                     (155 aa), FASTA scores: opt: 327, E(): 7.5e-14, (46.6%
                     identity in 133 aa overlap), also linked to glnA. Protein
                     product from Mb2243c detected using SWATH mass
                     spectrometry. Mb2243c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y0I9"
                     /db_xref="InterPro:IPR010432"
                     /db_xref="InterPro:IPR016795"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y0I9"
BEGIN
        1 MTAKSPPDYP GKTLGLPDTG PGSLAPMGRR LAALLIDWLI AYGLALLGVE FGVWSTPMLS
       61 TVVLVIWLLL GVAAVRLFGF TPGQLMLGLV VVAVGGRRPV GIGRLVVRGL LIGLVVPPLF
      121 TDSDGRGLHD RLTATAVVRR
//