LOCUS       SIU00849.1               311 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Probable
            lipoate biosynthesis protein A LipA protein.
ACCESSION   LT708304-2263
PROTEIN_ID  SIU00849.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="lipA"
                     /locus_tag="BQ2027_MB2241"
                     /note="Mb2241, lipA, len: 311 aa. Equivalent to Rv2218,
                     len: 311 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 311 aa overlap). Probable lipA, lipoic
                     acid synthetase, similar to e.g. SW:LIPA_HAEIN P44463 (42
                     .6% identity in 291 aa overlap). Equivalent to
                     Z98741|MLCB2 2_12 Mycobacterium leprae cosmid B22; (314
                     aa). FASTA score : opt: 1836, E(): 0; 86.8% identity in
                     310 aa overlap,Mb2241 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P65284"
                     /db_xref="InterPro:IPR003698"
                     /db_xref="InterPro:IPR006638"
                     /db_xref="InterPro:IPR007197"
                     /db_xref="InterPro:IPR013785"
                     /db_xref="InterPro:IPR031691"
                     /db_xref="UniProtKB/Swiss-Prot:P65284"
BEGIN
        1 MSVAAEGRRL LRLEVRNAQT PIERKPPWIK TRARIGPEYT ELKNLVRREG LHTVCEEAGC
       61 PNIFECWEDR EATFLIGGDQ CTRRCDFCQI DTGKPAELDR DEPRRVADSV RTMGLRYATV
      121 TGVARDDLPD GGAWLYAATV RAIKELNPST GVELLIPDFN GEPTRLAEVF ESGPEVLAHN
      181 VETVPRIFKR IRPAFTYRRS LGVLTAARDA GLVTKSNLIL GLGETSDEVR TALGDLRDAG
      241 CDIVTITQYL RPSARHHPVE RWVKPEEFVQ FARFAEGLGF AGVLAGPLVR SSYRAGRLYE
      301 QARNSRALAS R
//