LOCUS       SIU00848.1               230 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Probable
            lipoate biosynthesis protein B LipB protein.
ACCESSION   LT708304-2262
PROTEIN_ID  SIU00848.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="lipB"
                     /locus_tag="BQ2027_MB2240"
                     /note="Mb2240, lipB, len: 230 aa. Equivalent to Rv2217,
                     len: 230 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.6% identity in 230 aa overlap). Probable lipB, similar
                     to SW:LIPB_ECOLI P30976 liopate biosynthesis protein B
                     (33.8% identity in 160 aa overlap). Equivalent to
                     gp|Z98741| MLCB22_11 Mycobacterium leprae (235 aa). FASTA
                     score: opt: 1124, E(): 0; 78.4% identity in 218 aa overlap
                     Protein product from Mb2240 detected using SWATH mass
                     spectrometry. Mb2240 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:Q7VEN4"
                     /db_xref="InterPro:IPR000544"
                     /db_xref="InterPro:IPR004143"
                     /db_xref="InterPro:IPR020605"
                     /db_xref="UniProtKB/Swiss-Prot:Q7VEN4"
BEGIN
        1 MTGSIRSKLS AIDVRQLGTV DYRTAWQLQR ELADARVAGG ADTLLLLEHP AVYTAGRRTE
       61 THERPIDGTP VVGTDRGGKI TWHGPGQLVG YPIIGLAEPL DVVNYVRRLE ESLIQVCADL
      121 GLHAGRVDGR SGVWLPGRPA RKVAAIGVRV SRATTLHGFA LNCDCDLAAF TAIVPCGISD
      181 AAVTSLSAEL GRTVTVDEVR ATVAAAVCAA LDGVLPVGDR VPSHAVPSPL
//