LOCUS       SIU00841.1               368 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 branched-
            chain amino acid transaminase ilve protein.
ACCESSION   LT708304-2255
PROTEIN_ID  SIU00841.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="ilvE"
                     /locus_tag="BQ2027_MB2233C"
                     /note="Mb2233c, ilvE, len: 368 aa. Equivalent to Rv2210c,
                     len: 368 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 368 aa overlap). Probable ilvE,
                     Branched-chain-amino-acid transaminase, highly similar to
                     many e.g. YWAA_BACSU|P39576 from Bacillus subtilis (48.4%
                     identity in 339 aa overlap); etc. Protein product from
                     Mb2233c detected using shotgun mass spectrometry and SWATH
                     mass spectrometry. Mb2233c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y0I1"
                     /db_xref="InterPro:IPR001544"
                     /db_xref="InterPro:IPR005786"
                     /db_xref="InterPro:IPR018300"
                     /db_xref="InterPro:IPR033939"
                     /db_xref="InterPro:IPR036038"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y0I1"
BEGIN
        1 MTSGSLQFTV LRAVNPATDA QRESMLRAPG FGKYHTDHMV SIDYAEGRGW HNARVIPYGP
       61 IELDPSAIVL HYAQEVFEGL KAYRWADGSI VSFRADANAA RLRSSARRLA IPELPDAVFI
      121 ESLRQLIAVD KAWVPGAGGE EALYLRPFIF ATEPGLGVRP ATQYRYLLIA SPAGAYFKGG
      181 IAPVSVWVST EYVRACPGGT GAAKFGGNYA ASLLAQAEAA ENGCDQVVWL DAVERRYIEE
      241 MGGMNIFFVL GSGGSARLVT PELSGSLLPG ITRDSLLQLA IDAGFAVEER RIDIDEWQKK
      301 AAAGEITEVF ACGTAAVITP VARVRHGASE FRIADGQPGE VTMALRDTLT GIQRGTFADT
      361 HGWMARLG
//