LOCUS       SIU00836.1               358 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Glycerate
            kinase (EC protein.
ACCESSION   LT708304-2250
PROTEIN_ID  SIU00836.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2228C"
                     /EC_number="2.7.1.31"
                     /note="Mb2228c, -, len: 358 aa. Equivalent to Rv2205c,
                     len: 358 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 358 aa overlap). Conserved
                     hypothetical protein. Very similar to YHAD_ECOLI|P23524
                     hypothetical protein (YHAD (E.coli) / YXAA (S14A)
                     (B.subtilis) family) (41.6% identity in 154 aa overlap),
                     and to other members of the glycerate kinase family. Start
                     changed since first submission; protein now 122 aa
                     shorter, owing to extension of Rv2206. Mb2228c found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:P64289"
                     /db_xref="InterPro:IPR004381"
                     /db_xref="InterPro:IPR018193"
                     /db_xref="InterPro:IPR018197"
                     /db_xref="InterPro:IPR036129"
                     /db_xref="UniProtKB/Swiss-Prot:P64289"
BEGIN
        1 MRVLVAPDCY GDSLSAVEAA AAIATGWTRS RPGDSFIVAP QSDGGPGFVE VLGSRLGETR
       61 RLRVCGPLNT VVNAAWVFDP GSATAYLECA QACGLGLLGG PPTPETALAA HSKGVGQLIA
      121 AALRAGAARI VVGLGGSACT DGGKGMIAEL GGLDAARRQL ADVEVIAASD VEYPLLGPWG
      181 TARVFAPQKG ADMATVAVLE GRLAAWAIEL DAAAGRGVSA EPGAGAAGGI GAGLLAVGGR
      241 YQSGAAIIAE HTHFADDLAD AELIVTGEGR FDEQSLHGKV VGAIAAAARP LAIPVIVLAG
      301 QVSLDKSALR SAGIMAALSI AEYAGSVRLA LADAANQLMG LASQVAARLG NSGPSGYR
//