LOCUS SIU00836.1 358 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Glycerate kinase (EC protein. ACCESSION LT708304-2250 PROTEIN_ID SIU00836.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2228C" /EC_number="2.7.1.31" /note="Mb2228c, -, len: 358 aa. Equivalent to Rv2205c, len: 358 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 358 aa overlap). Conserved hypothetical protein. Very similar to YHAD_ECOLI|P23524 hypothetical protein (YHAD (E.coli) / YXAA (S14A) (B.subtilis) family) (41.6% identity in 154 aa overlap), and to other members of the glycerate kinase family. Start changed since first submission; protein now 122 aa shorter, owing to extension of Rv2206. Mb2228c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P64289" /db_xref="InterPro:IPR004381" /db_xref="InterPro:IPR018193" /db_xref="InterPro:IPR018197" /db_xref="InterPro:IPR036129" /db_xref="UniProtKB/Swiss-Prot:P64289" BEGIN 1 MRVLVAPDCY GDSLSAVEAA AAIATGWTRS RPGDSFIVAP QSDGGPGFVE VLGSRLGETR 61 RLRVCGPLNT VVNAAWVFDP GSATAYLECA QACGLGLLGG PPTPETALAA HSKGVGQLIA 121 AALRAGAARI VVGLGGSACT DGGKGMIAEL GGLDAARRQL ADVEVIAASD VEYPLLGPWG 181 TARVFAPQKG ADMATVAVLE GRLAAWAIEL DAAAGRGVSA EPGAGAAGGI GAGLLAVGGR 241 YQSGAAIIAE HTHFADDLAD AELIVTGEGR FDEQSLHGKV VGAIAAAARP LAIPVIVLAG 301 QVSLDKSALR SAGIMAALSI AEYAGSVRLA LADAANQLMG LASQVAARLG NSGPSGYR //