LOCUS       SIU00834.1               230 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            CONSERVED MEMBRANE PROTEIN protein.
ACCESSION   LT708304-2248
PROTEIN_ID  SIU00834.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2226"
                     /note="Mb2226, -, len: 230 aa. Equivalent to Rv2203, len:
                     230 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 230 aa overlap). Possible conserved
                     membrane protein; has single hydrophobic stretch from aa
                     75 to 97 and is equivalent to Mycobacterium leprae ML0872
                     putative membrane protein (171 aa). FASTA scores: opt:
                     821, E(): 3.4e-42; 72.353% identity in 170 aa overlap
                     -CAC31253.1| (AL583920). 2468411. Protein product from
                     Mb2226 detected using SWATH mass spectrometry. Mb2226
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:P64950"
                     /db_xref="UniProtKB/Swiss-Prot:P64950"
BEGIN
        1 MPGPHSPNPG VGTNGPAPYP EPSSHEPQAL DYPHDLGAAE PAFAPGPADD AALPPAAYPG
       61 VPPQVSYPKR RHKRLLIGIV VALALVSAMT AAIIYGVRTN GANTAGTFSE GPAKTAIQGY
      121 LNALENRDVD TIVRNALCGI HDGVRDKRSD QALAKLSSDA FRKQFSQVEV TSIDKIVYWS
      181 QYQAQVLFTM QVTPAAGGPP RGQVQGIAQL LFQRGQVLVC SYVLRTAGSY
//