LOCUS SIU00834.1 230 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE CONSERVED MEMBRANE PROTEIN protein. ACCESSION LT708304-2248 PROTEIN_ID SIU00834.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2226" /note="Mb2226, -, len: 230 aa. Equivalent to Rv2203, len: 230 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 230 aa overlap). Possible conserved membrane protein; has single hydrophobic stretch from aa 75 to 97 and is equivalent to Mycobacterium leprae ML0872 putative membrane protein (171 aa). FASTA scores: opt: 821, E(): 3.4e-42; 72.353% identity in 170 aa overlap -CAC31253.1| (AL583920). 2468411. Protein product from Mb2226 detected using SWATH mass spectrometry. Mb2226 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:P64950" /db_xref="UniProtKB/Swiss-Prot:P64950" BEGIN 1 MPGPHSPNPG VGTNGPAPYP EPSSHEPQAL DYPHDLGAAE PAFAPGPADD AALPPAAYPG 61 VPPQVSYPKR RHKRLLIGIV VALALVSAMT AAIIYGVRTN GANTAGTFSE GPAKTAIQGY 121 LNALENRDVD TIVRNALCGI HDGVRDKRSD QALAKLSSDA FRKQFSQVEV TSIDKIVYWS 181 QYQAQVLFTM QVTPAAGGPP RGQVQGIAQL LFQRGQVLVC SYVLRTAGSY //