LOCUS       SIU00826.1               429 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Probable
            Rieske iron-sulfur protein QcrA protein.
ACCESSION   LT708304-2240
PROTEIN_ID  SIU00826.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="qcrA"
                     /locus_tag="BQ2027_MB2218"
                     /note="Mb2218, qcrA, len: 429 aa. Equivalent to Rv2195,
                     len: 429 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.8% identity in 429 aa overlap). Probable qcrA,
                     Ubiquinol-cytochrome C reductase iron-sulfur subunit
                     (cyoB), shows some similarity to cytochrome B6-F complex
                     iron-sulphur subunits (Rieske iron-sulfur protein);
                     contains PS00200 Rieske iron-sulfur protein signature 2
                     Protein product from Mb2218 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb2218 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:Q7TYX4"
                     /db_xref="InterPro:IPR014349"
                     /db_xref="InterPro:IPR017941"
                     /db_xref="InterPro:IPR036922"
                     /db_xref="UniProtKB/Swiss-Prot:Q7TYX4"
BEGIN
        1 MSRADDDAVG VPPTCGGRSD EEERRIVPGP NPQDGAKDGA KATAVPREPD EAALAAMSNQ
       61 ELLALGGKLD GVRIAYKEPR WPVEGTKAEK RAERSVAVWL LLGGVFGLAL LLIFLFWPWE
      121 FKAADGESDF IYSLTTPLYG LTFGLSILSI AIGAVLYQKR FIPEEISIQE RHDGASREID
      181 RKTVVANLTD AFEGSTIRRR KLIGLSFGVG MGAFGLGTLV AFAGGLIKNP WKPVVPTAEG
      241 KKAVLWTSGW TPRYQGETIY LARATGTEDG PPFIKMRPED IDAGGMETVF PWRESDGDGT
      301 TVESHHKLQE IAMGIRNPVM LIRIKPSDLG RVVKRKGQES FNFGEFFAFT KVCSHLGCPS
      361 SLYEQQSYRI LCPCHQSQFD ALHFAKPIFG PAARALAQLP ITIDTDGYLV ANGDFVEPVG
      421 PAFWERTTT
//