LOCUS SIU00825.1 280 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Probable Ubiquinol-cytochrome C reductase QcrC (cytochrome C subunit) protein. ACCESSION LT708304-2239 PROTEIN_ID SIU00825.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="qcrC" /locus_tag="BQ2027_MB2217" /note="Mb2217, qcrC, len: 280 aa. Equivalent to Rv2194, len: 280 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 280 aa overlap). Probable qcrC, Ubiquinol-cytochrome C reductase cytochrome C subunit (cyoA), shows similarity to cytochrome c family; contains 2 X PS00190 Cytochrome c family heme-binding site signature. Protein product from Mb2217 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2217 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P63888" /db_xref="InterPro:IPR009056" /db_xref="InterPro:IPR009152" /db_xref="InterPro:IPR036909" /db_xref="UniProtKB/Swiss-Prot:P63888" BEGIN 1 MTKLGFTRSG GSKSGRTRRR LRRRLSGGVL LLIALTIAGG LAAVLTPTPQ VAVADESSSA 61 LLRTGKQLFD TSCVSCHGAN LQGVPDHGPS LIGVGEAAVY FQVSTGRMPA MRGEAQAPRK 121 DPIFDEAQID AIGAYVQANG GGPTVVRNPD GSIATQSLRG NDLGRGGDLF RLNCASCHNF 181 TGKGGALSSG KYAPDLAPAN EQQILTAMLT GPQNMPKFSN RQLSFEAKKD IIAYVKVATE 241 ARQPGGYLLG GFGPAPEGMA MWIIGMVAAI GLALWIGARS //