LOCUS       SIU00825.1               280 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Probable
            Ubiquinol-cytochrome C reductase QcrC (cytochrome C subunit)
            protein.
ACCESSION   LT708304-2239
PROTEIN_ID  SIU00825.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="qcrC"
                     /locus_tag="BQ2027_MB2217"
                     /note="Mb2217, qcrC, len: 280 aa. Equivalent to Rv2194,
                     len: 280 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 280 aa overlap). Probable qcrC,
                     Ubiquinol-cytochrome C reductase cytochrome C subunit
                     (cyoA), shows similarity to cytochrome c family; contains
                     2 X PS00190 Cytochrome c family heme-binding site
                     signature. Protein product from Mb2217 detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb2217 found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="GOA:P63888"
                     /db_xref="InterPro:IPR009056"
                     /db_xref="InterPro:IPR009152"
                     /db_xref="InterPro:IPR036909"
                     /db_xref="UniProtKB/Swiss-Prot:P63888"
BEGIN
        1 MTKLGFTRSG GSKSGRTRRR LRRRLSGGVL LLIALTIAGG LAAVLTPTPQ VAVADESSSA
       61 LLRTGKQLFD TSCVSCHGAN LQGVPDHGPS LIGVGEAAVY FQVSTGRMPA MRGEAQAPRK
      121 DPIFDEAQID AIGAYVQANG GGPTVVRNPD GSIATQSLRG NDLGRGGDLF RLNCASCHNF
      181 TGKGGALSSG KYAPDLAPAN EQQILTAMLT GPQNMPKFSN RQLSFEAKKD IIAYVKVATE
      241 ARQPGGYLLG GFGPAPEGMA MWIIGMVAAI GLALWIGARS
//