LOCUS SIU00824.1 203 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE CYTOCHROME C OXIDASE (SUBUNIT III) CTAE protein. ACCESSION LT708304-2238 PROTEIN_ID SIU00824.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="ctaE" /locus_tag="BQ2027_MB2216" /note="Mb2216, ctaE, len: 203 aa. Equivalent to Rv2193, len: 203 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 203 aa overlap). Probable ctaE, cytochrome c oxidase polypeptide III (cox3) (EC 1.9.3.1), with strong similarity to others e.g. COX3_SYNY3|Q06475 (29.8% identity in 225 aa overlap). Protein product from Mb2216 detected using SWATH mass spectrometry. Mb2216 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:P63857" /db_xref="InterPro:IPR000298" /db_xref="InterPro:IPR013833" /db_xref="InterPro:IPR024791" /db_xref="InterPro:IPR035973" /db_xref="UniProtKB/Swiss-Prot:P63857" BEGIN 1 MTSAVGTSGT AITSRVHSLN RPNMVSVGTI VWLSSELMFF AGLFAFYFSA RAQAGGNWPP 61 PPTELNLYQA VPVTLVLIAS SFTCQMGVFA AERGDIFGLR RWYVITFLMG LFFVLGQAYE 121 YRNLMSHGTS IPSSAYGSVF YLATGFHGLH VTGGLIAFIF LLVRTGMSKF TPAQATASIV 181 VSYYWHFVDI VWIALFTVIY FIR //