LOCUS       SIU00824.1               203 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CYTOCHROME C OXIDASE (SUBUNIT III) CTAE protein.
ACCESSION   LT708304-2238
PROTEIN_ID  SIU00824.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="ctaE"
                     /locus_tag="BQ2027_MB2216"
                     /note="Mb2216, ctaE, len: 203 aa. Equivalent to Rv2193,
                     len: 203 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 203 aa overlap). Probable ctaE,
                     cytochrome c oxidase polypeptide III (cox3) (EC 1.9.3.1),
                     with strong similarity to others e.g. COX3_SYNY3|Q06475
                     (29.8% identity in 225 aa overlap). Protein product from
                     Mb2216 detected using SWATH mass spectrometry. Mb2216
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:P63857"
                     /db_xref="InterPro:IPR000298"
                     /db_xref="InterPro:IPR013833"
                     /db_xref="InterPro:IPR024791"
                     /db_xref="InterPro:IPR035973"
                     /db_xref="UniProtKB/Swiss-Prot:P63857"
BEGIN
        1 MTSAVGTSGT AITSRVHSLN RPNMVSVGTI VWLSSELMFF AGLFAFYFSA RAQAGGNWPP
       61 PPTELNLYQA VPVTLVLIAS SFTCQMGVFA AERGDIFGLR RWYVITFLMG LFFVLGQAYE
      121 YRNLMSHGTS IPSSAYGSVF YLATGFHGLH VTGGLIAFIF LLVRTGMSKF TPAQATASIV
      181 VSYYWHFVDI VWIALFTVIY FIR
//