LOCUS       SIU00819.1               385 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 mannosyltransfera
            se pimb protein.
ACCESSION   LT708304-2233
PROTEIN_ID  SIU00819.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="pimb"
                     /locus_tag="BQ2027_MB2211C"
                     /note="Mb2211c, -, len: 385 aa. Equivalent to Rv2188c,
                     len: 385 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 385 aa overlap). Conserved
                     hypothetical protein, possibly glycosyl transferase
                     similar to several putative glycosyl transferases and
                     hypothetical proteins e.g. P73369. Equivalent to
                     Mycobacterium leprae ML0886 putative glycosyl transferase
                     (384 aa). FASTA scores: ML0886 (CAA18697.1| (AL022602))
                     opt: 2113, E(): 1.8e-106; 81.462% identity in 383 aa
                     overlap; sptr|P73369|P73369 HYPOTHETICAL 46.2 KD PROTEIN
                     (404 aa) opt: 379, E(): 2.2e-18; 27.5% identity in 397 aa
                     overlap. Start changed since first submission, now 14 aa
                     shorter. Protein product from Mb2211c detected using SWATH
                     mass spectrometry. Mb2211c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y0H8"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="InterPro:IPR028098"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y0H8"
BEGIN
        1 MSRVLLVTND FPPRRGGIQS YLGEFVGRLV GSRAHAMTVY APQWKGADAF DDAARAAGYR
       61 VVRHPSTVML PGPTVDVRMR RLIAEHDIET VWFGAAAPLA LLAPRARLAG ASRVLASTHG
      121 HEVGWSMLPV ARSVLRRIGD GTDVVTFVSS YTRSRFASAF GPAASLEYLP PGVDTDRFRP
      181 DPAARAELRK RYRLGERPTV VCLSRLVPRK GQDTLVTALP SIRRRVDGAA LVIVGGGPYL
      241 ETLRKLAHDC GVADHVTFTG GVATDELPAH HALADVFAMP CRTRGAGMDV EGLGIVFLEA
      301 SAAGVPVIAG NSGGAPETVQ HNKTGLVVDG RSVDRVADAV AELLIDRDRA VAMGAAGREW
      361 VTAQWRWDTL AAKLADFLRG DDAAR
//