LOCUS SIU00819.1 385 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 mannosyltransfera se pimb protein. ACCESSION LT708304-2233 PROTEIN_ID SIU00819.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="pimb" /locus_tag="BQ2027_MB2211C" /note="Mb2211c, -, len: 385 aa. Equivalent to Rv2188c, len: 385 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 385 aa overlap). Conserved hypothetical protein, possibly glycosyl transferase similar to several putative glycosyl transferases and hypothetical proteins e.g. P73369. Equivalent to Mycobacterium leprae ML0886 putative glycosyl transferase (384 aa). FASTA scores: ML0886 (CAA18697.1| (AL022602)) opt: 2113, E(): 1.8e-106; 81.462% identity in 383 aa overlap; sptr|P73369|P73369 HYPOTHETICAL 46.2 KD PROTEIN (404 aa) opt: 379, E(): 2.2e-18; 27.5% identity in 397 aa overlap. Start changed since first submission, now 14 aa shorter. Protein product from Mb2211c detected using SWATH mass spectrometry. Mb2211c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y0H8" /db_xref="InterPro:IPR001296" /db_xref="InterPro:IPR028098" /db_xref="UniProtKB/TrEMBL:A0A1R3Y0H8" BEGIN 1 MSRVLLVTND FPPRRGGIQS YLGEFVGRLV GSRAHAMTVY APQWKGADAF DDAARAAGYR 61 VVRHPSTVML PGPTVDVRMR RLIAEHDIET VWFGAAAPLA LLAPRARLAG ASRVLASTHG 121 HEVGWSMLPV ARSVLRRIGD GTDVVTFVSS YTRSRFASAF GPAASLEYLP PGVDTDRFRP 181 DPAARAELRK RYRLGERPTV VCLSRLVPRK GQDTLVTALP SIRRRVDGAA LVIVGGGPYL 241 ETLRKLAHDC GVADHVTFTG GVATDELPAH HALADVFAMP CRTRGAGMDV EGLGIVFLEA 301 SAAGVPVIAG NSGGAPETVQ HNKTGLVVDG RSVDRVADAV AELLIDRDRA VAMGAAGREW 361 VTAQWRWDTL AAKLADFLRG DDAAR //