LOCUS SIU00815.1 144 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Cyclase/ Dehydrase protein. ACCESSION LT708304-2229 PROTEIN_ID SIU00815.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="TB16.3" /locus_tag="BQ2027_MB2207C" /note="Mb2207c, TB16.3, len: 144 aa. Equivalent to Rv2185c, len: 144 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 144 aa overlap). TB16.3, conserved hypothetical protein, similar to other hypothetical actinomycete proteins and equivalent to Mycobacterium leprae ML0889 (144 aa). Some similarity to Mycobacterium tuberculosis Rv0854, Rv0856, Rv0857, Rv0164 and other Mycobacterium leprae proteins. FASTA scores : ML0889 opt: 811; 85.417% identity in 144 aa overlap (AL022602). Protein product from Mb2207c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2207c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR019587" /db_xref="InterPro:IPR023393" /db_xref="UniProtKB/TrEMBL:A0A1R3Y175" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MADKTTQTIY IDADPGEVMK AIADIEAYPQ WISEYKEVEI LEADDEGYPK RARMLMDAAI 61 FKDTLIMSYE WPEDRQSLSW TLESSSLLKS LEGTYRLAPK GSGTEVTYEL AVDLAVPMIG 121 MLKRKAERRL IDGALKDLKK RVEG //