LOCUS SIU00807.1 221 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE TRANSPOSASE protein. ACCESSION LT708304-2221 PROTEIN_ID SIU00807.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2199C" /note="Mb2199c, -, len: 221 aa. Equivalent to Rv2177c, len: 221 aa, from Mycobacterium tuberculosis strain H37Rv, (99.5% identity in 221 aa overlap). Possible IS1558 transposase (see citation below), similar to several IS element proteins and transposases but nearly identical to last 221 residues of MTCY428_23 (333 aa). FASTA scores: Z81451|MTCY428_23 Mycobacterium tuberculosis cosmid (333 aa) opt: 1491, E() : 0; 98.6% identity in 221 aa overlap. Mb2199c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:A0A1R3Y0U4" /db_xref="InterPro:IPR003346" /db_xref="UniProtKB/TrEMBL:A0A1R3Y0U4" BEGIN 1 MRSKIPDLQR ALEGRFDDHH ALMCRLHLAH LDQLDAMIGA LDEQIEQLMH PFCARRELIA 61 SIPGIGVGAS ATVISEIGAD PAAWFPSAEH LASWVRLCPG NHESAGKRHH GARRKGNQHL 121 QPVLVECAWA AVRTDGYLRE YYRRQVRKFG GFRSPAANKK AIIAVAHKLI VIIWHVLATG 181 RPYQDLGADY FTTRMDPDKE RRRLVAKLEA QGLGVTLEPA A //