LOCUS SIU00805.1 146 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 conserved regulatory protein protein. ACCESSION LT708304-2219 PROTEIN_ID SIU00805.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2197C" /note="Mb2197c, -, len: 146 aa. Equivalent to Rv2175c, len: 146 aa, from Mycobacterium tuberculosis strain H37Rv, (99.3% identity in 146 aa overlap). Conserved hypothetical protein, possibly involved in regulation. Contains possible helix-turn-helix domain at aa 31-52 (Score 1042, +2.74 SD). Equivalent to Mycobacterium leprae ML0898 putative DNA-binding protein (134 aa). FASTA scores: opt: 747; 82.090% identity in 134 aa overlap (AL022602) >gi|13092969|emb|CAC31279.1| (AL583920) Protein product from Mb2197c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2197c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR041098" /db_xref="UniProtKB/TrEMBL:A0A1R3Y164" BEGIN 1 MPGRAPGSTL ARVGSILAGD DVLDPDEPTY DLPRVAELLG VPVSKVAQQL REGHLVAVRR 61 AGGVVIPQVF FTNSGQVVKS LPGLLTILHD GGYRDTEIMR WLFTPDPSLT ITRDGSRDAV 121 SNARPVDALH AHQAREVVRR AQAMAY //