LOCUS       SIU00805.1               146 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 conserved
            regulatory protein protein.
ACCESSION   LT708304-2219
PROTEIN_ID  SIU00805.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2197C"
                     /note="Mb2197c, -, len: 146 aa. Equivalent to Rv2175c,
                     len: 146 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.3% identity in 146 aa overlap). Conserved hypothetical
                     protein, possibly involved in regulation. Contains
                     possible helix-turn-helix domain at aa 31-52 (Score 1042,
                     +2.74 SD). Equivalent to Mycobacterium leprae ML0898
                     putative DNA-binding protein (134 aa). FASTA scores: opt:
                     747; 82.090% identity in 134 aa overlap (AL022602)
                     >gi|13092969|emb|CAC31279.1| (AL583920) Protein product
                     from Mb2197c detected using shotgun mass spectrometry and
                     SWATH mass spectrometry. Mb2197c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR041098"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y164"
BEGIN
        1 MPGRAPGSTL ARVGSILAGD DVLDPDEPTY DLPRVAELLG VPVSKVAQQL REGHLVAVRR
       61 AGGVVIPQVF FTNSGQVVKS LPGLLTILHD GGYRDTEIMR WLFTPDPSLT ITRDGSRDAV
      121 SNARPVDALH AHQAREVVRR AQAMAY
//