LOCUS       SIU00788.1               359 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 probable
            phospho-n-acetylmuramoyl- pentappeptidetransferase murx
            protein.
ACCESSION   LT708304-2202
PROTEIN_ID  SIU00788.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="murX"
                     /locus_tag="BQ2027_MB2180C"
                     /note="Mb2180c, murX, len: 359 aa. Equivalent to Rv2156c,
                     len: 359 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 359 aa overlap). Probable murX,
                     phospho-N-acetylmuramoyl-pentappeptidetransferase (EC
                     2.7.8 .13). FASTA best: MRAY_ECOLI P15876 (360 aa) opt:
                     572 z-sco re: 651.6 E(): 2.7e-29; (35.8% identity in 344
                     aa overlap) Protein product from Mb2180c detected using
                     SWATH mass spectrometry. Mb2180c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P64260"
                     /db_xref="InterPro:IPR000715"
                     /db_xref="InterPro:IPR003524"
                     /db_xref="InterPro:IPR018480"
                     /db_xref="UniProtKB/Swiss-Prot:P64260"
BEGIN
        1 MRQILIAVAV AVTVSILLTP VLIRLFTKQG FGHQIREDGP PSHHTKRGTP SMGGVAILAG
       61 IWAGYLGAHL AGLAFDGEGI GASGLLVLGL ATALGGVGFI DDLIKIRRSR NLGLNKTAKT
      121 VGQITSAVLF GVLVLQFRNA AGLTPGSADL SYVREIATVT LAPVLFVLFC VVIVSAWSNA
      181 VNFTDGLDGL AAGTMAMVTA AYVLITFWQY RNACVTAPGL GCYNVRDPLD LALIAAATAG
      241 ACIGFLWWNA APAKIFMGDT GSLALGGVIA GLSVTSRTEI LAVVLGALFV AEITSVVLQI
      301 LTFRTTGRRM FRMAPFHHHF ELVGWAETTV IIRFWLLTAI TCGLGVALFY GEWLAAVGA
//