LOCUS SIU00788.1 359 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 probable phospho-n-acetylmuramoyl- pentappeptidetransferase murx protein. ACCESSION LT708304-2202 PROTEIN_ID SIU00788.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="murX" /locus_tag="BQ2027_MB2180C" /note="Mb2180c, murX, len: 359 aa. Equivalent to Rv2156c, len: 359 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 359 aa overlap). Probable murX, phospho-N-acetylmuramoyl-pentappeptidetransferase (EC 2.7.8 .13). FASTA best: MRAY_ECOLI P15876 (360 aa) opt: 572 z-sco re: 651.6 E(): 2.7e-29; (35.8% identity in 344 aa overlap) Protein product from Mb2180c detected using SWATH mass spectrometry. Mb2180c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P64260" /db_xref="InterPro:IPR000715" /db_xref="InterPro:IPR003524" /db_xref="InterPro:IPR018480" /db_xref="UniProtKB/Swiss-Prot:P64260" BEGIN 1 MRQILIAVAV AVTVSILLTP VLIRLFTKQG FGHQIREDGP PSHHTKRGTP SMGGVAILAG 61 IWAGYLGAHL AGLAFDGEGI GASGLLVLGL ATALGGVGFI DDLIKIRRSR NLGLNKTAKT 121 VGQITSAVLF GVLVLQFRNA AGLTPGSADL SYVREIATVT LAPVLFVLFC VVIVSAWSNA 181 VNFTDGLDGL AAGTMAMVTA AYVLITFWQY RNACVTAPGL GCYNVRDPLD LALIAAATAG 241 ACIGFLWWNA APAKIFMGDT GSLALGGVIA GLSVTSRTEI LAVVLGALFV AEITSVVLQI 301 LTFRTTGRRM FRMAPFHHHF ELVGWAETTV IIRFWLLTAI TCGLGVALFY GEWLAAVGA //