LOCUS       SIU00777.1               260 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 diviva
            family protein wag31 protein.
ACCESSION   LT708304-2191
PROTEIN_ID  SIU00777.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="wag31"
                     /locus_tag="BQ2027_MB2169C"
                     /standard_name="ag84"
                     /note="Mb2169c, wag31, len: 260 aa. Equivalent to Rv2145c,
                     len: 260 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 260 aa overlap). wag31 (alternate gene
                     name: ag84). Function unknown but corresponds to antigen
                     84 of Mycobacterium tuberculosis (wag31) (see first
                     citation below). Predicted to contain significant amount
                     of coiled coil structure. Some similarity to Rv1682 and
                     Rv2927c. FASTA best: AG84_MYCTU P46816 antigen 84. Protein
                     product from Mb2169c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb2169c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:P0A5N3"
                     /db_xref="InterPro:IPR007793"
                     /db_xref="InterPro:IPR019933"
                     /db_xref="UniProtKB/Swiss-Prot:P0A5N3"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MPLTPADVHN VAFSKPPIGK RGYNEDEVDA FLDLVENELT RLIEENSDLR QRINELDQEL
       61 AAGGGAGVTP QATQAIPAYE PEPGKPAPAA VSAGMNEEQA LKAARVLSLA QDTADRLTNT
      121 AKAESDKMLA DARANAEQIL GEARHTADAT VAEARQRADA MLADAQSRSE AQLRQAQEKA
      181 DALQADAERK HSEIMGTINQ QRAVLEGRLE QLRTFEREYR TRLKTYLESQ LEELGQRGSA
      241 APVDSNADAG GFDQFNRGKN
//