LOCUS       SIU00772.1               448 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 YscS-
            like amidohydrolase protein.
ACCESSION   LT708304-2186
PROTEIN_ID  SIU00772.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2165C"
                     /note="Mb2165c, -, len: 448 aa. Equivalent to Rv2141c,
                     len: 448 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 448 aa overlap). Conserved
                     hypothetical protein. Shows some similarity to conserved
                     hypothetical proteins and to acetylornithine deacetylase
                     and succinyl-diaminopimelate desuccinylase and contains
                     ArgE/dapE/ACY1/CPG2/yscS family signature 1 (PS00758).
                     FASTA best: CBPS_YEAST P27614 carboxypeptidases precursor
                     (576 aa) opt: 234, E(): 4.3e-08; (24.3% identity in 412 aa
                     overlap). Previously named dapE2 Protein product from
                     Mb2165c detected using shotgun mass spectrometry and SWATH
                     mass spectrometry. Mb2165c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y0E1"
                     /db_xref="InterPro:IPR001261"
                     /db_xref="InterPro:IPR002933"
                     /db_xref="InterPro:IPR011650"
                     /db_xref="InterPro:IPR036264"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y0E1"
BEGIN
        1 MTDETGASSD HSDDVAQVVS RLIRFDTTNS GEPGTTKGEA ECARWVAEQL AEVGYQPEYV
       61 ESGAPGRGNV FARLAGADSS RGALLIHGHL DVVPAEPAEW SVHPFSGAIE DGYVWGRGAV
      121 DMKDMVGMMI VVARHLRQAA IVPPRDLVFA FVADEEHGGK YGSHWLVDNR PDLFDGITEA
      181 IGEVGGFSLT VPRHDGGERR LYLIETAEKG IQWMRLTARG RAGHGSMVHD QNAVTAVCEA
      241 VARLGRHQFP LVCTDTVAQF LAVVGEETGL AFDLDSPDLA GTIDKLGPMA RMLKAVLHDT
      301 ANPTMLKAGY KANVVPATAE AVVDCRVLPG RRAAFEAEVD ALIGPDVTRE WVSDLPSYET
      361 TFDGDLVAAM NAAVLAVDPD GRTVPYMLSG GTDAKAFARL GIRCFGFSPL RLPPDLDFTS
      421 LFHGVDERVP IDGLRFGTEV LTHLLTHC
//