LOCUS SIU00772.1 448 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 YscS- like amidohydrolase protein. ACCESSION LT708304-2186 PROTEIN_ID SIU00772.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2165C" /note="Mb2165c, -, len: 448 aa. Equivalent to Rv2141c, len: 448 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 448 aa overlap). Conserved hypothetical protein. Shows some similarity to conserved hypothetical proteins and to acetylornithine deacetylase and succinyl-diaminopimelate desuccinylase and contains ArgE/dapE/ACY1/CPG2/yscS family signature 1 (PS00758). FASTA best: CBPS_YEAST P27614 carboxypeptidases precursor (576 aa) opt: 234, E(): 4.3e-08; (24.3% identity in 412 aa overlap). Previously named dapE2 Protein product from Mb2165c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2165c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y0E1" /db_xref="InterPro:IPR001261" /db_xref="InterPro:IPR002933" /db_xref="InterPro:IPR011650" /db_xref="InterPro:IPR036264" /db_xref="UniProtKB/TrEMBL:A0A1R3Y0E1" BEGIN 1 MTDETGASSD HSDDVAQVVS RLIRFDTTNS GEPGTTKGEA ECARWVAEQL AEVGYQPEYV 61 ESGAPGRGNV FARLAGADSS RGALLIHGHL DVVPAEPAEW SVHPFSGAIE DGYVWGRGAV 121 DMKDMVGMMI VVARHLRQAA IVPPRDLVFA FVADEEHGGK YGSHWLVDNR PDLFDGITEA 181 IGEVGGFSLT VPRHDGGERR LYLIETAEKG IQWMRLTARG RAGHGSMVHD QNAVTAVCEA 241 VARLGRHQFP LVCTDTVAQF LAVVGEETGL AFDLDSPDLA GTIDKLGPMA RMLKAVLHDT 301 ANPTMLKAGY KANVVPATAE AVVDCRVLPG RRAAFEAEVD ALIGPDVTRE WVSDLPSYET 361 TFDGDLVAAM NAAVLAVDPD GRTVPYMLSG GTDAKAFARL GIRCFGFSPL RLPPDLDFTS 421 LFHGVDERVP IDGLRFGTEV LTHLLTHC //