LOCUS SIU00769.1 358 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Probable conserved lipoprotein LppL protein. ACCESSION LT708304-2183 PROTEIN_ID SIU00769.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="lppL" /locus_tag="BQ2027_MB2162" /note="Mb2162, lppL, len: 358 aa. Equivalent to Rv2138, len: 358 aa, from Mycobacterium tuberculosis strain H37Rv, (99.2% identity in 358 aa overlap). Probable lppL, conserved lipoprotein, with appropriately placed lipoprotein signature (PS00013) strongly similar to hypothetical Mycobacterium leprae protein, Q49806. FASTA best: Q49806 B2126_F3_142. (298 aa) opt: 1495, E(): 0; (75.3% identity in 300 aa overlap). Protein product from Mb2162 detected using SWATH mass spectrometry. Mb2162 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="InterPro:IPR015943" /db_xref="UniProtKB/TrEMBL:A0A1R3Y0D3" BEGIN 1 MLTGNKPAVQ RRFIGLLMLS VLVAGCSSNP LANFAPGYPP TIEPAQPAVS PPTSQDPAGA 61 VRPLSGHPRA ALFDNGTRQL VALRPGADSA APASIMVFDD VHVAPRVIFL PGPAAALTSD 121 DHGTAFLAAR GGYFVADLSS GHTARVNVAD AAHTDFTAIA RRSDGKLVLG SADGAVYTLA 181 KNPAVDPASG AATVASRTKI FARVDALVTQ GNTTVVLDRG QTSVTTIGAD GHAQQALRAG 241 QGATTMAADP LGRVLIADTR GGQLLVYGVD PLILRQAYPV RQAPYGLAGS RELAWVSQTA 301 SNTVIGYDLT TGIPVEKVRY PTVQQPNSLA FDETSDTLYV VSGSGAGVQV IEHAAGTR //