LOCUS       SIU00769.1               358 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Probable
            conserved lipoprotein LppL protein.
ACCESSION   LT708304-2183
PROTEIN_ID  SIU00769.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="lppL"
                     /locus_tag="BQ2027_MB2162"
                     /note="Mb2162, lppL, len: 358 aa. Equivalent to Rv2138,
                     len: 358 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.2% identity in 358 aa overlap). Probable lppL,
                     conserved lipoprotein, with appropriately placed
                     lipoprotein signature (PS00013) strongly similar to
                     hypothetical Mycobacterium leprae protein, Q49806. FASTA
                     best: Q49806 B2126_F3_142. (298 aa) opt: 1495, E(): 0;
                     (75.3% identity in 300 aa overlap). Protein product from
                     Mb2162 detected using SWATH mass spectrometry. Mb2162
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="InterPro:IPR015943"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y0D3"
BEGIN
        1 MLTGNKPAVQ RRFIGLLMLS VLVAGCSSNP LANFAPGYPP TIEPAQPAVS PPTSQDPAGA
       61 VRPLSGHPRA ALFDNGTRQL VALRPGADSA APASIMVFDD VHVAPRVIFL PGPAAALTSD
      121 DHGTAFLAAR GGYFVADLSS GHTARVNVAD AAHTDFTAIA RRSDGKLVLG SADGAVYTLA
      181 KNPAVDPASG AATVASRTKI FARVDALVTQ GNTTVVLDRG QTSVTTIGAD GHAQQALRAG
      241 QGATTMAADP LGRVLIADTR GGQLLVYGVD PLILRQAYPV RQAPYGLAGS RELAWVSQTA
      301 SNTVIGYDLT TGIPVEKVRY PTVQQPNSLA FDETSDTLYV VSGSGAGVQV IEHAAGTR
//