LOCUS       SIU00766.1               236 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Phosphoglycerate 
            mutase family protein protein.
ACCESSION   LT708304-2180
PROTEIN_ID  SIU00766.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2159C"
                     /note="Mb2159c, -, len: 236 aa. Equivalent to Rv2135c,
                     len: 236 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 236 aa overlap). Conserved
                     hypothetical protein. Function: unknown but equivalent to
                     hypothetical Mycobacterium leprae protein, Q49773. FASTA
                     best: Q49773 B2126_C1_148 opt: 1183, E() : 0; (74.8%
                     identity in 250 aa overlap), also similar in C-terminus to
                     PMG2_ECOLI P36942 probable phosphoglycerate mutase 2 (215
                     aa), FASTA scores; opt: 212, E(): 2.5e-07 27.9% identity
                     in 190 aa overlap; and to Rv2228 and Rv2419c Protein
                     product from Mb2159c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb2159c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="InterPro:IPR013078"
                     /db_xref="InterPro:IPR022492"
                     /db_xref="InterPro:IPR029033"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y0E8"
BEGIN
        1 MTVILLRHAR STSNTAGVLA GRSGVDLDEK GREQATGLID RIGDLPIRAV ASSPMLRCQR
       61 TVEPLAEALC LEPLIDDRFS EVDYGEWTGR KIGDLVDEPL WRVVQAHPSA AVFPGGEGLA
      121 QVQTRAVAAV REHDRRLADQ HGHDVLWLAC THGDVIKAVI ADAFGMHLDS FQRITADPGS
      181 VSVVRYTQLR PFVLHVNHTG ARLAPALQAA ASAQGASPEP NAAVPPGDAV IGGSTD
//