LOCUS SIU00766.1 236 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Phosphoglycerate mutase family protein protein. ACCESSION LT708304-2180 PROTEIN_ID SIU00766.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2159C" /note="Mb2159c, -, len: 236 aa. Equivalent to Rv2135c, len: 236 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 236 aa overlap). Conserved hypothetical protein. Function: unknown but equivalent to hypothetical Mycobacterium leprae protein, Q49773. FASTA best: Q49773 B2126_C1_148 opt: 1183, E() : 0; (74.8% identity in 250 aa overlap), also similar in C-terminus to PMG2_ECOLI P36942 probable phosphoglycerate mutase 2 (215 aa), FASTA scores; opt: 212, E(): 2.5e-07 27.9% identity in 190 aa overlap; and to Rv2228 and Rv2419c Protein product from Mb2159c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2159c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="InterPro:IPR013078" /db_xref="InterPro:IPR022492" /db_xref="InterPro:IPR029033" /db_xref="UniProtKB/TrEMBL:A0A1R3Y0E8" BEGIN 1 MTVILLRHAR STSNTAGVLA GRSGVDLDEK GREQATGLID RIGDLPIRAV ASSPMLRCQR 61 TVEPLAEALC LEPLIDDRFS EVDYGEWTGR KIGDLVDEPL WRVVQAHPSA AVFPGGEGLA 121 QVQTRAVAAV REHDRRLADQ HGHDVLWLAC THGDVIKAVI ADAFGMHLDS FQRITADPGS 181 VSVVRYTQLR PFVLHVNHTG ARLAPALQAA ASAQGASPEP NAAVPPGDAV IGGSTD //