LOCUS SIU00736.1 144 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 possible toxin vapc37. contains pin domain. protein. ACCESSION LT708304-2150 PROTEIN_ID SIU00736.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="vapc37" /locus_tag="BQ2027_MB2129C" /note="Mb2129c, -, len: 144 aa. Equivalent to Rv2103c, len: 144 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 144 aa overlap). Conserved hypothetical protein, similar to hypothetical mycobacterial proteins belonging to family, includes Rv0749, Rv0277c, Rv2530c, Rv3320c, Rv2494, Rv2872, Rv0617, Rv1242 etc. FASTA scores: sptr|Q49793|Q49793 B2126_C3_261 (97 aa) opt: 331, E(): 4.8e-18; 59.4% identity in 96 aa overlap and gp|Z74024|MTCY274_3 Mycobacterium tuberculosis cosmid (147 aa) opt: 234, E(): 1.2e-10; 34.8% identity in 141 aa overlap. Protein product from Mb2129c detected using shotgun mass spectrometry. Mb2129c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y089" /db_xref="InterPro:IPR002716" /db_xref="InterPro:IPR006226" /db_xref="InterPro:IPR022907" /db_xref="InterPro:IPR029060" /db_xref="UniProtKB/TrEMBL:A0A1R3Y089" BEGIN 1 MKIVDANVLL YAVNTTSEHH KPSLRWLDGA LSGADRVGFA WVPLLAFVRL ATKVGLFPRP 61 LPREAAITQV ADWLAAPSAV LVNPTVRHAD ILARMLTYVG TGANLVNDAH LAALAVEHRA 121 SIVSYDSDFG RFEGVRWDQP PALL //