LOCUS       SIU00736.1               144 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 possible
            toxin vapc37. contains pin domain. protein.
ACCESSION   LT708304-2150
PROTEIN_ID  SIU00736.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="vapc37"
                     /locus_tag="BQ2027_MB2129C"
                     /note="Mb2129c, -, len: 144 aa. Equivalent to Rv2103c,
                     len: 144 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 144 aa overlap). Conserved
                     hypothetical protein, similar to hypothetical
                     mycobacterial proteins belonging to family, includes
                     Rv0749, Rv0277c, Rv2530c, Rv3320c, Rv2494, Rv2872, Rv0617,
                     Rv1242 etc. FASTA scores: sptr|Q49793|Q49793 B2126_C3_261
                     (97 aa) opt: 331, E(): 4.8e-18; 59.4% identity in 96 aa
                     overlap and gp|Z74024|MTCY274_3 Mycobacterium tuberculosis
                     cosmid (147 aa) opt: 234, E(): 1.2e-10; 34.8% identity in
                     141 aa overlap. Protein product from Mb2129c detected
                     using shotgun mass spectrometry. Mb2129c found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y089"
                     /db_xref="InterPro:IPR002716"
                     /db_xref="InterPro:IPR006226"
                     /db_xref="InterPro:IPR022907"
                     /db_xref="InterPro:IPR029060"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y089"
BEGIN
        1 MKIVDANVLL YAVNTTSEHH KPSLRWLDGA LSGADRVGFA WVPLLAFVRL ATKVGLFPRP
       61 LPREAAITQV ADWLAAPSAV LVNPTVRHAD ILARMLTYVG TGANLVNDAH LAALAVEHRA
      121 SIVSYDSDFG RFEGVRWDQP PALL
//