LOCUS SIU00727.1 308 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 sec- independent protein translocase transmembrane protein tatc protein. ACCESSION LT708304-2141 PROTEIN_ID SIU00727.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="tatC" /locus_tag="BQ2027_MB2120C" /note="Mb2120c, tatC, len: 308 aa. Equivalent to Rv2093c, len: 308 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 308 aa overlap). Probable tatC, transmembrane protein, component of twin-arginine translocation protein export system (see citation below for more information), equivalent to U00017|U00017_1 from Mycobacterium leprae (317 aa), FASTA scores: opt: 1722, E(): 0, (84.5% identity in 310 aa overlap). Similarity to others e.g. P27857|TATC_ECOLI|MTTB|B3839|Z5360|ECS4768 Sec-independent protein translocase protein from E. coli strain K12 and O157:H7 (258 aa), FASTA scores: opt: 344, E(): 6e-16, (32.5% identity in 265 aa overlap). BELONGS TO THE TATC FAMILY. Protein product from Mb2120c detected using SWATH mass spectrometry. Mb2120c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P66896" /db_xref="InterPro:IPR002033" /db_xref="InterPro:IPR019820" /db_xref="UniProtKB/Swiss-Prot:P66896" BEGIN 1 MRAAGLLKRL NPRNRRSRVN PDATMSLVDH LTELRTRLLI SLAAILVTTI FGFVWYSHSI 61 FGLDSLGEWL RHPYCALPQS ARADISADGE CRLLATAPFD QFMLRLKVGM AAGIVLACPV 121 WFYQLWAFIT PGLYQRERRF AVAFVIPAAV LFVAGAVLAY LVLSKALGFL LTVGSDVQVT 181 ALSGDRYFGF LLNLLVVFGV SFEFPLLIVM LNLAGLLTYE RLKSWRRGLI FAMFVFAAIF 241 TPGSDPFSMT ALGAALTVLL ELAIQIARVH DKRKAKREAA IPDDEASVID PPSPVPAPSV 301 IGSHDDVT //