LOCUS       SIU00727.1               308 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 sec-
            independent protein translocase transmembrane protein
            tatc protein.
ACCESSION   LT708304-2141
PROTEIN_ID  SIU00727.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="tatC"
                     /locus_tag="BQ2027_MB2120C"
                     /note="Mb2120c, tatC, len: 308 aa. Equivalent to Rv2093c,
                     len: 308 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 308 aa overlap). Probable tatC,
                     transmembrane protein, component of twin-arginine
                     translocation protein export system (see citation below
                     for more information), equivalent to U00017|U00017_1 from
                     Mycobacterium leprae (317 aa), FASTA scores: opt: 1722,
                     E(): 0, (84.5% identity in 310 aa overlap). Similarity to
                     others e.g. P27857|TATC_ECOLI|MTTB|B3839|Z5360|ECS4768
                     Sec-independent protein translocase protein from E. coli
                     strain K12 and O157:H7 (258 aa), FASTA scores: opt: 344,
                     E(): 6e-16, (32.5% identity in 265 aa overlap). BELONGS TO
                     THE TATC FAMILY. Protein product from Mb2120c detected
                     using SWATH mass spectrometry. Mb2120c found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:P66896"
                     /db_xref="InterPro:IPR002033"
                     /db_xref="InterPro:IPR019820"
                     /db_xref="UniProtKB/Swiss-Prot:P66896"
BEGIN
        1 MRAAGLLKRL NPRNRRSRVN PDATMSLVDH LTELRTRLLI SLAAILVTTI FGFVWYSHSI
       61 FGLDSLGEWL RHPYCALPQS ARADISADGE CRLLATAPFD QFMLRLKVGM AAGIVLACPV
      121 WFYQLWAFIT PGLYQRERRF AVAFVIPAAV LFVAGAVLAY LVLSKALGFL LTVGSDVQVT
      181 ALSGDRYFGF LLNLLVVFGV SFEFPLLIVM LNLAGLLTYE RLKSWRRGLI FAMFVFAAIF
      241 TPGSDPFSMT ALGAALTVLL ELAIQIARVH DKRKAKREAA IPDDEASVID PPSPVPAPSV
      301 IGSHDDVT
//