LOCUS       SIU00687.1               237 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Dienelactone
            hydrolase family protein protein.
ACCESSION   LT708304-2100
PROTEIN_ID  SIU00687.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2080"
                     /note="Mb2080, -, len: 237 aa. Equivalent to Rv2054, len:
                     237 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 237 aa overlap). Conserved
                     hypothetical protein, some similarity to various
                     carboxymethylenebutenolidases e.g. sp|O67988|CLCD_RHOOP
                     CARBOXYMETHYLENEBUTENOLIDASE (DIENELACTONE HYDROLASE)
                     (DLH) >gi|2935034|gb|AAC38252.1| (AF003948) dienelactone
                     hydrolase [Rhodococcus opacus] Smith-Waterman scores:
                     Length = 252, Expect = 4e-08 Identities = 62/217 (28%).
                     Also similar to Rv2765. Protein product from Mb2080
                     detected using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb2080 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y0F5"
                     /db_xref="InterPro:IPR002925"
                     /db_xref="InterPro:IPR029058"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y0F5"
BEGIN
        1 MTTIEIDAPA GPIDALLGLP PGQGPWPGVV VVHDAVGYVP DNKLISERIA RAGYVVLTPN
       61 MYARGGRARC ITRVFRELLT KRGRALDDIL AARDHLLAMP ECSGRVGIVG FCMGGQFALV
      121 LSPRGFGATA PFYGTPLPRH LSETLNGACP IVASFGTRDP LGIGAANRLR KVTAAKNIPA
      181 DIKSYPGAGH SFANKLPGQP LVRIAGFGYN EAATEDAWRR VFEFFGQHLR AGSPGEP
//