LOCUS SIU00687.1 237 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Dienelactone hydrolase family protein protein. ACCESSION LT708304-2100 PROTEIN_ID SIU00687.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2080" /note="Mb2080, -, len: 237 aa. Equivalent to Rv2054, len: 237 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 237 aa overlap). Conserved hypothetical protein, some similarity to various carboxymethylenebutenolidases e.g. sp|O67988|CLCD_RHOOP CARBOXYMETHYLENEBUTENOLIDASE (DIENELACTONE HYDROLASE) (DLH) >gi|2935034|gb|AAC38252.1| (AF003948) dienelactone hydrolase [Rhodococcus opacus] Smith-Waterman scores: Length = 252, Expect = 4e-08 Identities = 62/217 (28%). Also similar to Rv2765. Protein product from Mb2080 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2080 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y0F5" /db_xref="InterPro:IPR002925" /db_xref="InterPro:IPR029058" /db_xref="UniProtKB/TrEMBL:A0A1R3Y0F5" BEGIN 1 MTTIEIDAPA GPIDALLGLP PGQGPWPGVV VVHDAVGYVP DNKLISERIA RAGYVVLTPN 61 MYARGGRARC ITRVFRELLT KRGRALDDIL AARDHLLAMP ECSGRVGIVG FCMGGQFALV 121 LSPRGFGATA PFYGTPLPRH LSETLNGACP IVASFGTRDP LGIGAANRLR KVTAAKNIPA 181 DIKSYPGAGH SFANKLPGQP LVRIAGFGYN EAATEDAWRR VFEFFGQHLR AGSPGEP //