LOCUS       SIU00671.1               357 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Probable
            sugar-transport ATP-binding protein ABC transporter protein.
ACCESSION   LT708304-2084
PROTEIN_ID  SIU00671.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2064C"
                     /note="Mb2064c, -, len: 357 aa. Equivalent to Rv2038c,
                     len: 357 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 357 aa overlap). Probable
                     sugar-transport ATP-binding protein ABC transporter (see
                     citation below), equivalent to
                     MLCB2052.30|Z98604|MLCB2052_15 from Mycobacterium leprae
                     (356 aa), FASTA scores: opt: 1866, E(): 0, (79.7% identity
                     in 355 aa overlap). Also similar to multiple sugar import
                     proteins e.g. Y08921|SRMSIK_1 msiK protein from
                     Streptomyces reticuli (377 aa), FASTA scores: opt: 1336,
                     E(): 0, (62.6% identity in 377 aa overlap); etc. Also
                     similar to several proteins from Mycobacterium
                     tuberculosis e.g. Rv2832c, Rv1238, Rv2397c, Rv3758c.
                     Contains PS00211 ABC transporters family signature and
                     PS00017 ATP/GTP-binding site motif A (P-loop). BELONGS TO
                     THE ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC
                     TRANSPORTERS). Mb2064c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y000"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR008995"
                     /db_xref="InterPro:IPR017871"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="InterPro:IPR040582"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y000"
BEGIN
        1 MASVSFEQAT RRYPGTDRPA LDRLDLIVGD GEFVVLVGPS GCGKTTSLRM VAGLETLDCG
       61 RIRIGERDVT EVDPKDRDVA MVFQNYALYP HMTVAQNMGF ALKVAKIGKA EIRERVLAAA
      121 KLLDLQSYLD RKPKDLSGGQ RQRVAMGRAI VRRPQVFLMD EPLSNLDAKL RGQTRNQIAA
      181 LQRQLGTTTV YVTHDQVEAM TMGDRVAVLS DGVLQQCASP RELYRNPGNV FVAGFIGSPA
      241 MNLFRLSIAD STVSLGDWQI LLPRAVVGTA AEVIIGVRPE HLELGGAGIE MDVDMVEELG
      301 ADAYLYGRIV SGGCEMDQSI VARVDGRGPP ERGSRVRLCP TPGHLHFFAV DGRRIPG
//