LOCUS SIU00671.1 357 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Probable sugar-transport ATP-binding protein ABC transporter protein. ACCESSION LT708304-2084 PROTEIN_ID SIU00671.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2064C" /note="Mb2064c, -, len: 357 aa. Equivalent to Rv2038c, len: 357 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 357 aa overlap). Probable sugar-transport ATP-binding protein ABC transporter (see citation below), equivalent to MLCB2052.30|Z98604|MLCB2052_15 from Mycobacterium leprae (356 aa), FASTA scores: opt: 1866, E(): 0, (79.7% identity in 355 aa overlap). Also similar to multiple sugar import proteins e.g. Y08921|SRMSIK_1 msiK protein from Streptomyces reticuli (377 aa), FASTA scores: opt: 1336, E(): 0, (62.6% identity in 377 aa overlap); etc. Also similar to several proteins from Mycobacterium tuberculosis e.g. Rv2832c, Rv1238, Rv2397c, Rv3758c. Contains PS00211 ABC transporters family signature and PS00017 ATP/GTP-binding site motif A (P-loop). BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS). Mb2064c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y000" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR008995" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR040582" /db_xref="UniProtKB/TrEMBL:A0A1R3Y000" BEGIN 1 MASVSFEQAT RRYPGTDRPA LDRLDLIVGD GEFVVLVGPS GCGKTTSLRM VAGLETLDCG 61 RIRIGERDVT EVDPKDRDVA MVFQNYALYP HMTVAQNMGF ALKVAKIGKA EIRERVLAAA 121 KLLDLQSYLD RKPKDLSGGQ RQRVAMGRAI VRRPQVFLMD EPLSNLDAKL RGQTRNQIAA 181 LQRQLGTTTV YVTHDQVEAM TMGDRVAVLS DGVLQQCASP RELYRNPGNV FVAGFIGSPA 241 MNLFRLSIAD STVSLGDWQI LLPRAVVGTA AEVIIGVRPE HLELGGAGIE MDVDMVEELG 301 ADAYLYGRIV SGGCEMDQSI VARVDGRGPP ERGSRVRLCP TPGHLHFFAV DGRRIPG //