LOCUS SIU00665.1 331 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Dinucleotide- utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 protein. ACCESSION LT708304-2078 PROTEIN_ID SIU00665.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="acg" /locus_tag="BQ2027_MB2058" /note="Mb2058, -, len: 331 aa. Equivalent to Rv2032, len: 331 aa, from Mycobacterium tuberculosis strain H37Rv, (99.7% identity in 331 aa overlap). acg (for acr-coregulated gene), conserved hypothetical protein possibly member of a superfamily of classical nitroreductases (see first citation below), similar to hypothetical mycobacterial proteins Rv3127|MTCY164.37 (344 aa) and Rv3131|MTCY03A2.27c (332 aa). FASTA scores: Z95150|MTCY164_38 Mycobacterium tuberculosis cosmid (344 aa) opt: 1208, E(): 0, (56.4% identity in 321 aa overlap); Z83867| MTCY3A2_27 Mycobacterium tuberculosis cosmid (332 aa) opt: 568, E(): 8.6e-30, (36.8% identity in 321 aa overlap). Similar to proteins SCJ1.11 (330 aa; AL109962) and SCJ12.27c (335 aa; AL109989) in Streptomyces coelicolor. Protein product from Mb2058 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2058 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y0T1" /db_xref="InterPro:IPR000415" /db_xref="UniProtKB/TrEMBL:A0A1R3Y0T1" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MPDTMVTTDV IKSAVQLACR APSLHNSQPW RWIAEDHTVA LFLDKDRVLY ATDHSGREAL 61 LGCGAVLDHF RVAMAAAGTT ANVERFPNPN DPLHLASIDF SPADFVTEGH RLRADAILLR 121 RTDRLPFAEP PDWDLVESQL RTTVTADTVR IDVIADDMRP ELAAASKLTE SLRLYDSSYH 181 AELFWWTGAF ETSEGIPHSS LVSAAESDRV TFGRDFPVVA NTDRRPEFGH DRSKVLVLST 241 YDNERASLLR CGEMLSAVLL DATMAGLATC TLTHITELHA SRDLVAALIG QPATPQALVR 301 VGLAPEMEEP PPATPRRLID EVFHVRAKDH R //