LOCUS       SIU00661.1               339 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 6-phosphofructoki
            nase pfkb (phosphohexokinase) (phosphofructokinase) protein.
ACCESSION   LT708304-2074
PROTEIN_ID  SIU00661.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="pfkB"
                     /locus_tag="BQ2027_MB2054C"
                     /note="Mb2054c, pfkB, len: 339 aa. Equivalent to Rv2029c,
                     len: 339 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 339 aa overlap). Probable pfkB,
                     phosphofructokinase (EC 2.7.1.-), similar to others eg
                     P06999|K6P2_ECOLI 6-PHOSPHOFRUCTOKINASE I SOZYME 2 from E.
                     coli (309 aa), FASTA scores: opt: 705, E(): 0; (41.4%
                     identity in 304 aa overlap); and LACC_STRMU
                     phosphotagatosekinase (310 aa); etc. Contains PS00583 pfkB
                     family of carbohydrate kinases signature 1. Protein
                     product from Mb2054c detected using SWATH mass
                     spectrometry."
                     /db_xref="GOA:A0A1R3XZZ1"
                     /db_xref="InterPro:IPR002173"
                     /db_xref="InterPro:IPR011611"
                     /db_xref="InterPro:IPR017583"
                     /db_xref="InterPro:IPR029056"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZZ1"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MTEPAAWDEG KPRIITLTMN PALDITTSVD VVRPTEKMRC GAPRYDPGGG GINVARIVHV
       61 LGGCSTALFP AGGSTGSLLM ALLGDAGVPF RVIPIAASTR ESFTVNESRT AKQYRFVLPG
      121 PSLTVAEQEQ CLDELRGAAA SAAFVVASGS LPPGVAADYY QRVADICRRS STPLILDTSG
      181 GGLQHISSGV FLLKASVREL RECVGSELLT EPEQLAAAHE LIDRGRAEVV VVSLGSQGAL
      241 LATRHASHRF SSIPMTAVSG VGAGDAMVAA ITVGLSRGWS LIKSVRLGNA AGAAMLLTPG
      301 TAACNRDDVE RFFELAAEPT EVGQDQYVWH PIVNPEASP
//