LOCUS       SIU00652.1               201 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Toxin
            HigB protein.
ACCESSION   LT708304-2065
PROTEIN_ID  SIU00652.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="higB2"
                     /locus_tag="BQ2027_MB2045C"
                     /note="Mb2045c, -, len: 201 aa. Equivalent to Rv2022c,
                     len: 201 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 201 aa overlap). Conserved
                     hypothetical protein, similar to Mycobacterium
                     tuberculosis hypothetical protein Rv3182, MTV014.26
                     (EMBL:AL 021646). FASTA scores; TR:E1248773 (114 aa) opt:
                     335, E(): 3e-22, 53.8% identity in 106 aa overlap and to
                     hypothetical proteins from Yersinia pestis (115 aa) e.g.
                     emb|CAB53172.1| (AL109969), 41% identity in 108 aa
                     overlap. Protein product from Mb2045c detected using
                     shotgun mass spectrometry. Mb2045c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR009241"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y021"
BEGIN
        1 MNVPWENAHG GALYCLIRGD EFSAWHRLLF QRPGCAESVL ACRHFLDGSP VARCSYPEEY
       61 HPCVISRIAL LCDSVGWTAD VERISAWLNG LDRETYELVF AAIEVLEEEG PALGCPLVDT
      121 VRGSRHKNMK ELRPGSQGRS EVRILFAFDP ARQAIMLAAG NKAGRWTQWY DEKIKAADEM
      181 FAEHLAQFED TKPKRRKRKK G
//