LOCUS SIU00652.1 201 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Toxin HigB protein. ACCESSION LT708304-2065 PROTEIN_ID SIU00652.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="higB2" /locus_tag="BQ2027_MB2045C" /note="Mb2045c, -, len: 201 aa. Equivalent to Rv2022c, len: 201 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 201 aa overlap). Conserved hypothetical protein, similar to Mycobacterium tuberculosis hypothetical protein Rv3182, MTV014.26 (EMBL:AL 021646). FASTA scores; TR:E1248773 (114 aa) opt: 335, E(): 3e-22, 53.8% identity in 106 aa overlap and to hypothetical proteins from Yersinia pestis (115 aa) e.g. emb|CAB53172.1| (AL109969), 41% identity in 108 aa overlap. Protein product from Mb2045c detected using shotgun mass spectrometry. Mb2045c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR009241" /db_xref="UniProtKB/TrEMBL:A0A1R3Y021" BEGIN 1 MNVPWENAHG GALYCLIRGD EFSAWHRLLF QRPGCAESVL ACRHFLDGSP VARCSYPEEY 61 HPCVISRIAL LCDSVGWTAD VERISAWLNG LDRETYELVF AAIEVLEEEG PALGCPLVDT 121 VRGSRHKNMK ELRPGSQGRS EVRILFAFDP ARQAIMLAAG NKAGRWTQWY DEKIKAADEM 181 FAEHLAQFED TKPKRRKRKK G //