LOCUS       SIU00648.1               239 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Putative
            antitoxin VapB45 protein.
ACCESSION   LT708304-2061
PROTEIN_ID  SIU00648.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="vapB45"
                     /locus_tag="BQ2027_MB2041"
                     /note="Mb2041, -, len: 239 aa. Equivalent to Rv2018, len:
                     239 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.6% identity in 239 aa overlap). Conserved hypothetical
                     protein, similar to Rv2308|MTCY339.01c (238 aa). FASTA
                     scores: Z77163|MTCY339_1 Mycobacterium tuberculosis cosmid
                     (238 aa) opt: 142, E(): 0.029; (24.8% identity in 250 aa
                     overlap). Contains probable helix-turn-helix motif at aa
                     215-236 (Score 1175, +3.19 SD). Protein product from
                     Mb2041 detected using shotgun mass spectrometry and SWATH
                     mass spectrometry. Mb2041 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XZX8"
                     /db_xref="InterPro:IPR007367"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR017277"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZX8"
BEGIN
        1 MAGDQELELR FDVPLYTLAE ASRYLVVPRA TLATWADGYE RRPANAPAVQ GQPIITALPH
       61 PTGSHARLPF VGIAEAYVLN AFRRAGVPMQ RIRPSLDWLI KNVGPHALAS QDLCTGGAEV
      121 LWRFAERSGE GSPDDLVVRG LIVPRSGQYV FKEIVEHYLQ QISFADDNLA SMIRLPQYGD
      181 ANVVLDPRRG YGQPVFDGSG VRVADVLGPL RAGATFQAVA DDYGVTPDQL RDALDAIAA
//