LOCUS SIU00648.1 239 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Putative antitoxin VapB45 protein. ACCESSION LT708304-2061 PROTEIN_ID SIU00648.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="vapB45" /locus_tag="BQ2027_MB2041" /note="Mb2041, -, len: 239 aa. Equivalent to Rv2018, len: 239 aa, from Mycobacterium tuberculosis strain H37Rv, (99.6% identity in 239 aa overlap). Conserved hypothetical protein, similar to Rv2308|MTCY339.01c (238 aa). FASTA scores: Z77163|MTCY339_1 Mycobacterium tuberculosis cosmid (238 aa) opt: 142, E(): 0.029; (24.8% identity in 250 aa overlap). Contains probable helix-turn-helix motif at aa 215-236 (Score 1175, +3.19 SD). Protein product from Mb2041 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2041 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XZX8" /db_xref="InterPro:IPR007367" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR017277" /db_xref="UniProtKB/TrEMBL:A0A1R3XZX8" BEGIN 1 MAGDQELELR FDVPLYTLAE ASRYLVVPRA TLATWADGYE RRPANAPAVQ GQPIITALPH 61 PTGSHARLPF VGIAEAYVLN AFRRAGVPMQ RIRPSLDWLI KNVGPHALAS QDLCTGGAEV 121 LWRFAERSGE GSPDDLVVRG LIVPRSGQYV FKEIVEHYLQ QISFADDNLA SMIRLPQYGD 181 ANVVLDPRRG YGQPVFDGSG VRVADVLGPL RAGATFQAVA DDYGVTPDQL RDALDAIAA //