LOCUS SIU00638.1 441 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 ATPase, AAA family protein. ACCESSION LT708304-2051 PROTEIN_ID SIU00638.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2031C" /note="Mb2031c, -, len: 441 aa. Equivalent to Rv2008c, len: 441 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 441 aa overlap). Conserved hypothetical protein. Contains PS00017 ATP/GTP-binding site motif A, PS00501 Signal peptidases I serine active site. Also contains helix-turn-helix motif at aa 258-279. Similar to several conserved hypothetical proteins e.g. NP_085874.1|14028123|dbj|BAB54715.1 hypothetical protein from Mesorhizobium loti (435 aa). Smith-Waterman score: 1e-74, Identities = 158/359 (44%) Protein product from Mb2031c detected using SWATH mass spectrometry." /db_xref="GOA:P64924" /db_xref="InterPro:IPR025420" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR041682" /db_xref="UniProtKB/Swiss-Prot:P64924" BEGIN 1 MDEIESLIGL RPTPLTWPVV IAGDFLGVWD PPPSLPGAAN HEISAPTARI SCMLIERRDA 61 AARLRRALHR APVVLLTGPR QAGKTTLSRL VGKSAPECTF DAENPVDATR LADPMLALSG 121 LSGLITIDEA QRIPDLFPVL RVLVDRPVMP ARFLILGSAS PDLVGLASES LAGRVELVEL 181 SGLTVRDVGS SAADRLWLRG GLPPSFTARS NEDSAAWRDG YITTFLERDL AQLGVRIPAA 241 TMRRAWTMLA HYHGQLFSGA ELARSLDVAQ TTARRYLDAL TDALVVRQLT PWFANIGKRQ 301 RRSPKIYIRD TGLLHRLLGI DDRLALERNP KLGASWEGFV LEQLAALLAP NPLYYWRTQQ 361 DAELDLYVEL SGRPYGFEIK RTSTPSISRS MRSALVDLQL ARLAIVYPGE HRFPLSDTVV 421 AVPADQILTT GSVDELLALL K //