LOCUS       SIU00638.1               441 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 ATPase,
            AAA family protein.
ACCESSION   LT708304-2051
PROTEIN_ID  SIU00638.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2031C"
                     /note="Mb2031c, -, len: 441 aa. Equivalent to Rv2008c,
                     len: 441 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 441 aa overlap). Conserved
                     hypothetical protein. Contains PS00017 ATP/GTP-binding
                     site motif A, PS00501 Signal peptidases I serine active
                     site. Also contains helix-turn-helix motif at aa 258-279.
                     Similar to several conserved hypothetical proteins e.g.
                     NP_085874.1|14028123|dbj|BAB54715.1 hypothetical protein
                     from Mesorhizobium loti (435 aa). Smith-Waterman score:
                     1e-74, Identities = 158/359 (44%) Protein product from
                     Mb2031c detected using SWATH mass spectrometry."
                     /db_xref="GOA:P64924"
                     /db_xref="InterPro:IPR025420"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="InterPro:IPR041682"
                     /db_xref="UniProtKB/Swiss-Prot:P64924"
BEGIN
        1 MDEIESLIGL RPTPLTWPVV IAGDFLGVWD PPPSLPGAAN HEISAPTARI SCMLIERRDA
       61 AARLRRALHR APVVLLTGPR QAGKTTLSRL VGKSAPECTF DAENPVDATR LADPMLALSG
      121 LSGLITIDEA QRIPDLFPVL RVLVDRPVMP ARFLILGSAS PDLVGLASES LAGRVELVEL
      181 SGLTVRDVGS SAADRLWLRG GLPPSFTARS NEDSAAWRDG YITTFLERDL AQLGVRIPAA
      241 TMRRAWTMLA HYHGQLFSGA ELARSLDVAQ TTARRYLDAL TDALVVRQLT PWFANIGKRQ
      301 RRSPKIYIRD TGLLHRLLGI DDRLALERNP KLGASWEGFV LEQLAALLAP NPLYYWRTQQ
      361 DAELDLYVEL SGRPYGFEIK RTSTPSISRS MRSALVDLQL ARLAIVYPGE HRFPLSDTVV
      421 AVPADQILTT GSVDELLALL K
//