LOCUS       SIU00634.1               498 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Predicted
            kinase protein.
ACCESSION   LT708304-2047
PROTEIN_ID  SIU00634.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2027C"
                     /note="Mb2027c, -, len: 498 aa. Equivalent to Rv2004c,
                     len: 498 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 498 aa overlap). Conserved
                     hypothetical protein similar to several e.g. >pir||T36945
                     hypothetical protein SCJ1.12 (508 aa) - Streptomyces
                     coelicolor >gi|5748625|emb|CAB53130.1| (AL109962).
                     Smith-Waterman score: 7e-94, Identities = 199/468 (42%).
                     Contains PS00017 ATP/GTP-binding site motif A. Protein
                     product from Mb2027c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb2027c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:P0A5G0"
                     /db_xref="InterPro:IPR011009"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/Swiss-Prot:P0A5G0"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MDSPTNDGTC DAHPVTDEPF IDVRETHTAV VVLAGDRAFK AKKPVVTDFC DFRTAEQRER
       61 ACIREFELNS RLAAQSYLGI AHLSDPSGGH AEPVVVMRRY RDKQRLASMV TAGLPVEGAL
      121 DAIAEVLARF HQRAQRNRCI DTQGEVGAVA RRWHENLAEL RHHADKVVSG DVIRRIEHMV
      181 DEFVSGREVL FAGRIKEGCI VDGHADLLAD DIFLVDGEPA LLDCLEFEDE LRYLDRIDDA
      241 AFLAMDLEFL GRKDLGDYFL AGYAVRSGDT APASLRDFYI AYRAVVRAKV ECVRFSQGKP
      301 EAAADAVRHL IIATQHLQHA TVRLALVGGN PGTGKSTLAR GVAELVGAQV ISTDDVRRRL
      361 RDCGVITGEP GVLDSGLYSR ANVVAVYQEA LRKARLLLGS GHSVILDGTW GDPQMRACAR
      421 RLAADTHSAI VEFRCSATVD VMADRIVARA GGNSDATAEI AAALAARQAD WDTGHRIDTA
      481 GPRERSVGQA YHIWRSAI
//