LOCUS SIU00634.1 498 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Predicted kinase protein. ACCESSION LT708304-2047 PROTEIN_ID SIU00634.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2027C" /note="Mb2027c, -, len: 498 aa. Equivalent to Rv2004c, len: 498 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 498 aa overlap). Conserved hypothetical protein similar to several e.g. >pir||T36945 hypothetical protein SCJ1.12 (508 aa) - Streptomyces coelicolor >gi|5748625|emb|CAB53130.1| (AL109962). Smith-Waterman score: 7e-94, Identities = 199/468 (42%). Contains PS00017 ATP/GTP-binding site motif A. Protein product from Mb2027c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2027c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:P0A5G0" /db_xref="InterPro:IPR011009" /db_xref="InterPro:IPR027417" /db_xref="UniProtKB/Swiss-Prot:P0A5G0" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MDSPTNDGTC DAHPVTDEPF IDVRETHTAV VVLAGDRAFK AKKPVVTDFC DFRTAEQRER 61 ACIREFELNS RLAAQSYLGI AHLSDPSGGH AEPVVVMRRY RDKQRLASMV TAGLPVEGAL 121 DAIAEVLARF HQRAQRNRCI DTQGEVGAVA RRWHENLAEL RHHADKVVSG DVIRRIEHMV 181 DEFVSGREVL FAGRIKEGCI VDGHADLLAD DIFLVDGEPA LLDCLEFEDE LRYLDRIDDA 241 AFLAMDLEFL GRKDLGDYFL AGYAVRSGDT APASLRDFYI AYRAVVRAKV ECVRFSQGKP 301 EAAADAVRHL IIATQHLQHA TVRLALVGGN PGTGKSTLAR GVAELVGAQV ISTDDVRRRL 361 RDCGVITGEP GVLDSGLYSR ANVVAVYQEA LRKARLLLGS GHSVILDGTW GDPQMRACAR 421 RLAADTHSAI VEFRCSATVD VMADRIVARA GGNSDATAEI AAALAARQAD WDTGHRIDTA 481 GPRERSVGQA YHIWRSAI //