LOCUS SIU00628.1 258 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PEP phosphonomutase and related enzymes protein. ACCESSION LT708304-2041 PROTEIN_ID SIU00628.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2021C" /note="Mb2021c, -, len: 258 aa. Equivalent to Rv1998c, len: 258 aa, from Mycobacterium tuberculosis strain H37Rv, (99.6% identity in 258 aa overlap). Conserved hypothetical protein, showing some similarity with other hypothetical proteins e.g. U82823|SEU82823.03 Saccharopolyspora erythraea (266 aa), FASTA results: opt: 654, E(): 0, (43.8% identity in 249 aa overlap); and AL034446|SC1A9.07 Streptomyces coelicolor (251 aa), FASTA scores: opt: 592, E(): 1.5e-31, (43.4% identity in 251 aa overlap). Protein product from Mb2021c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2021c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:A0A1R3XZW5" /db_xref="InterPro:IPR015813" /db_xref="InterPro:IPR039556" /db_xref="InterPro:IPR040442" /db_xref="UniProtKB/TrEMBL:A0A1R3XZW5" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MSFHDLHHQG VPFVLPNAWD VPSALAYLAE GFTAIGTTSF GVSSSGGHPD GHRATRGANI 61 ALAAALAPLQ CYVSVDIEDG YSDEPDAIAD YVAQLSTAGI NIEDSSAEKL IDPALAAAKI 121 VAIKQRNPEV FVNARVDTYW LRQHADTTST IQRALRYVDA GADGVFVPLA NDPDELAELT 181 RNIPCPVNTL PVPGLTIADL GELGVARVST GSVPYSAGLY AAAHAARAVR DGEQLPRSVP 241 YAELQARLVD YENRTSTT //