LOCUS       SIU00628.1               258 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PEP
            phosphonomutase and related enzymes protein.
ACCESSION   LT708304-2041
PROTEIN_ID  SIU00628.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2021C"
                     /note="Mb2021c, -, len: 258 aa. Equivalent to Rv1998c,
                     len: 258 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.6% identity in 258 aa overlap). Conserved hypothetical
                     protein, showing some similarity with other hypothetical
                     proteins e.g. U82823|SEU82823.03 Saccharopolyspora
                     erythraea (266 aa), FASTA results: opt: 654, E(): 0,
                     (43.8% identity in 249 aa overlap); and AL034446|SC1A9.07
                     Streptomyces coelicolor (251 aa), FASTA scores: opt: 592,
                     E(): 1.5e-31, (43.4% identity in 251 aa overlap). Protein
                     product from Mb2021c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb2021c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3XZW5"
                     /db_xref="InterPro:IPR015813"
                     /db_xref="InterPro:IPR039556"
                     /db_xref="InterPro:IPR040442"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZW5"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MSFHDLHHQG VPFVLPNAWD VPSALAYLAE GFTAIGTTSF GVSSSGGHPD GHRATRGANI
       61 ALAAALAPLQ CYVSVDIEDG YSDEPDAIAD YVAQLSTAGI NIEDSSAEKL IDPALAAAKI
      121 VAIKQRNPEV FVNARVDTYW LRQHADTTST IQRALRYVDA GADGVFVPLA NDPDELAELT
      181 RNIPCPVNTL PVPGLTIADL GELGVARVST GSVPYSAGLY AAAHAARAVR DGEQLPRSVP
      241 YAELQARLVD YENRTSTT
//