LOCUS       SIU00627.1               905 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            METAL CATION TRANSPORTER P-TYPE ATPASE A CTPF protein.
ACCESSION   LT708304-2040
PROTEIN_ID  SIU00627.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="ctpF"
                     /locus_tag="BQ2027_MB2020"
                     /note="Mb2020, ctpF, len: 905 aa. Equivalent to Rv1997,
                     len: 905 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 905 aa overlap). Probable ctpF, metal
                     cation-transporting P-type ATPase F (transmembrane
                     protein) (EC 3.6.3.-), highly similar to others e.g.
                     NP_250120.1|NC_002516 probable cation-transporting P-type
                     ATPase from Pseudomonas aeruginosa (902 aa);
                     NP_441217.1|NC_000911 cation-transporting ATPase (E1-E2
                     ATPase) from Synechocystis sp. strain PCC 6803 (905 aa);
                     NP_404093.1|NC_003143 putative cation-transporting P-type
                     ATPase from Yersinia pestis (908 aa); P37367|ATA1_SYNY3
                     cation-transporting ATPase pma1 from Synechocystis sp.
                     (915 aa), FASTA scores: opt: 2392, E(): 0, (46.5% identity
                     in 852 aa overlap); etc. Contains PS00154 E1-E2 ATPases
                     phosphorylation site. BELONGS TO THE CATION TRANSPORT
                     ATPASES FAMILY (E1-E2 ATPASES), SUBFAMILY IB. Was
                     frame-shifted in original cosmid sequence. Protein product
                     from Mb2020 detected using SWATH mass spectrometry. Mb2020
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="GOA:P63688"
                     /db_xref="InterPro:IPR001757"
                     /db_xref="InterPro:IPR004014"
                     /db_xref="InterPro:IPR006068"
                     /db_xref="InterPro:IPR008250"
                     /db_xref="InterPro:IPR018303"
                     /db_xref="InterPro:IPR023214"
                     /db_xref="InterPro:IPR023298"
                     /db_xref="InterPro:IPR023299"
                     /db_xref="InterPro:IPR036412"
                     /db_xref="UniProtKB/Swiss-Prot:P63688"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MSASVSATTA HHGLPAHEVV LLLESDPYHG LSDGEAAQRL ERFGPNTLAV VTRASLLARI
       61 LRQFHHPLIY VLLVAGTITA GLKEFVDAAV IFGVVVINAI VGFIQESKAE AALQGLRSMV
      121 HTHAKVVREG HEHTMPSEEL VPGDLVLLAA GDKVPADLRL VRQTGLSVNE SALTGESTPV
      181 HKDEVALPEG TPVADRRNIA YSGTLVTAGH GAGIVVATGA ETELGEIHRL VGAAEVVATP
      241 LTAKLAWFSK FLTIAILGLA ALTFGVGLLR RQDAVETFTA AIALAVGAIP EGLPTAVTIT
      301 LAIGMARMAK RRAVIRRLPA VETLGSTTVI CADKTGTLTE NQMTVQSIWT PHGEIRATGT
      361 GYAPDVLLCD TDDAPVPVNA NAALRWSLLA GACSNDAALV RDGTRWQIVG DPTEGAMLVV
      421 AAKAGFNPER LATTLPQVAA IPFSSERQYM ATLHRDGTDH VVLAKGAVER MLDLCGTEMG
      481 ADGALRPLDR ATVLRATEML TSRGLRVLAT GMGAGAGTPD DFDENVIPGS LALTGLQAMS
      541 DPPRAAAASA VAACHSAGIA VKMITGDHAG TATAIATEVG LLDNTEPAAG SVLTGAELAA
      601 LSADQYPEAV DTASVFARVS PEQKLRLVQA LQARGHVVAM TGDGVNDAPA LRQANIGVAM
      661 GRGGTEVAKD AADMVLTDDD FATIEAAVEE GRGVFDNLTK FITWTLPTNL GEGLVILAAI
      721 AVGVALPILP TQILWINMTT AIALGLMLAF EPKEAGIMTR PPRDPDQPLL TGWLVRRTLL
      781 VSTLLVASAW WLFAWELDNG AGLHEARTAA LNLFVVVEAF YLFSCRSLTR SAWRLGMFAN
      841 RWIILGVSAQ AIAQFAITYL PAMNMVFDTA PIDIGVWVRI FAVATAITIV VATDTLLPRI
      901 RAQPP
//