LOCUS       SIU00621.1                82 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Antitoxin
            MazE6 protein.
ACCESSION   LT708304-2034
PROTEIN_ID  SIU00621.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="mazE6"
                     /locus_tag="BQ2027_MB2014A"
                     /note="Mb2014A, len: 82 aa. Equivalent to Rv1991A len: 82
                     aa, from Mycobacterium tuberculosis strain H37Rv, (100.0%
                     identity in 82 aa overlap). Transferred from H37Rv
                     annotation using Rapid Annotation Transfer Tool (Nucleic
                     Acids Res. 2011 May; 39(9): e57). MazE6, antitoxin, part
                     of toxin-antitoxin (TA) operon with Rv1991c. Similar to
                     ChpI of L. interrogans, FASTA scores: opt: 134, E():
                     0.024,29.762% identity (65.476% similar) in 84 aa overlap.
                     Note that Pandey and Gerdes, 2005 predicts a different
                     N-terminus, adding 10 amino acids. Mb2014A found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:P0CL58"
                     /db_xref="InterPro:IPR002145"
                     /db_xref="InterPro:IPR010985"
                     /db_xref="UniProtKB/Swiss-Prot:P0CL58"
BEGIN
        1 MKTAISLPDE TFDRVSRRAS ELGMSRSEFF TKAAQRYLHE LDAQLLTGQI DRALESIHGT
       61 DEAEALAVAN AYRVLETMDD EW
//