LOCUS       SIU00614.1               199 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED INTEGRAL MEMBRANE PROTEIN protein.
ACCESSION   LT708304-2027
PROTEIN_ID  SIU00614.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2008"
                     /note="Mb2008, -, len: 199 aa. Equivalent to Rv1986, len:
                     199 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 199 aa overlap). Probable conserved
                     integral membrane protein, LysE family possibly involved
                     in transport of Lysine, similar to P11667|YGGA_ECOLI
                     hypothetical 23.2 kd protein in sbm-fba intergenic region
                     (211 aa), FASTA scores: opt: 379, E(): 1.5e-19, (37.3%
                     identity in 185 aa overlap); and Q11154|Rv0488
                     HYPOTHETICAL 20.9 KD PROTEIN from Mycobacterium
                     tuberculosis (201 aa), FASTA scores: opt: 784, E(): 0,
                     (63.4% identity in 186 aa overlap). BELONGS TO THE
                     LYSE/YGGA FAMILY. Mb2008 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P64904"
                     /db_xref="InterPro:IPR001123"
                     /db_xref="InterPro:IPR004777"
                     /db_xref="UniProtKB/Swiss-Prot:P64904"
BEGIN
        1 MNSPLVVGFL ACFTLIAAIG AQNAFVLRQG IQREHVLPVV ALCTVSDIVL IAAGIAGFGA
       61 LIGAHPRALN VVKFGGAAFL IGYGLLAARR AWRPVALIPS GATPVRLAEV LVTCAAFTFL
      121 NPHVYLDTVV LLGALANEHS DQRWLFGLGA VTASAVWFAT LGFGAGRLRG LFTNPGSWRI
      181 LDGLIAVMMV ALGISLTVT
//