LOCUS SIU00614.1 199 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN protein. ACCESSION LT708304-2027 PROTEIN_ID SIU00614.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2008" /note="Mb2008, -, len: 199 aa. Equivalent to Rv1986, len: 199 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 199 aa overlap). Probable conserved integral membrane protein, LysE family possibly involved in transport of Lysine, similar to P11667|YGGA_ECOLI hypothetical 23.2 kd protein in sbm-fba intergenic region (211 aa), FASTA scores: opt: 379, E(): 1.5e-19, (37.3% identity in 185 aa overlap); and Q11154|Rv0488 HYPOTHETICAL 20.9 KD PROTEIN from Mycobacterium tuberculosis (201 aa), FASTA scores: opt: 784, E(): 0, (63.4% identity in 186 aa overlap). BELONGS TO THE LYSE/YGGA FAMILY. Mb2008 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P64904" /db_xref="InterPro:IPR001123" /db_xref="InterPro:IPR004777" /db_xref="UniProtKB/Swiss-Prot:P64904" BEGIN 1 MNSPLVVGFL ACFTLIAAIG AQNAFVLRQG IQREHVLPVV ALCTVSDIVL IAAGIAGFGA 61 LIGAHPRALN VVKFGGAAFL IGYGLLAARR AWRPVALIPS GATPVRLAEV LVTCAAFTFL 121 NPHVYLDTVV LLGALANEHS DQRWLFGLGA VTASAVWFAT LGFGAGRLRG LFTNPGSWRI 181 LDGLIAVMMV ALGISLTVT //