LOCUS       SIU00606.1               481 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            CONSERVED PERMEASE protein.
ACCESSION   LT708304-2019
PROTEIN_ID  SIU00606.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2001C"
                     /note="Mb2001c, -, len: 481 aa. Equivalent to Rv1979c,
                     len: 481 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.6% identity in 480 aa overlap). Possible permease, APC
                     family possibly involved in transport of amino acid,
                     showing some similarity to other permeases. Also similar
                     to MTCY39.19 from Mycobacterium tuberculosis (28.2%
                     identity in 277 aa overlap). Contains PS00599
                     Aminotransferases class-II pyridoxal-phosphate attachment
                     site. Mb2001c found to be expressed during exponential
                     growth in Sauton's minimal media by RNA-sequencing (TPM >
                     20)."
                     /db_xref="GOA:Q7TZ67"
                     /db_xref="InterPro:IPR002293"
                     /db_xref="UniProtKB/Swiss-Prot:Q7TZ67"
BEGIN
        1 MVGPRTRGYA IHKLGFCSVV MLGINSIIGA GIFLTPGEVI GLAGPFAPMA YVLAGIFAGV
       61 VAIVFATAAR YVRTNGASYA YTTAAFGRRI GIYVGVTHAI TASIAWGVLA SFFVSTLLRV
      121 AFPDKAWADA EQLFSVKTLT FLGFIGVLLA INLFGNRAIK WANGTSTVGK AFALSAFIVG
      181 GLWIITTQHV NNYATAWSAY SATPYSLLGV AEIGKGTFSS MALATIVALY AFTGFESIAN
      241 AAEEMDAPDR NLPRAIPIAI FSVGAIYLLT LTVAMLLGSN KIAASGDTVK LAAAIGNATF
      301 RTIIVVGALI SMFGINVAAS FGAPRLWTAL ADSGVLPTRL SRKNQYDVPM VSFAITASLA
      361 LAFPLALRFD NLHLTGLAVI ARFVQFIIVP IALIALARSQ AVEHAAVRRN AFTDKVLPLV
      421 AIVVSVGLAV SYDYRCIFLV RGGPNYFSIA LIVITFIVVP AMAYLHYYRI IRRVGDRPST
      481 R
//