LOCUS       SIU00580.1               109 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 possible
            toxin mazf5 protein.
ACCESSION   LT708304-1993
PROTEIN_ID  SIU00580.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="mazf5"
                     /locus_tag="BQ2027_MB1977C"
                     /note="Mb1977c, -, len: 109 aa. Equivalent to Rv1942c,
                     len: 109 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 109 aa overlap). Conserved
                     hypothetical protein, shows some similarity to
                     Q10867|MTCY39.28|Rv1991 hypothetical 12.3 kd protein (114
                     aa), FASTA scores: opt: 117, E(): 0.021, (24. 5% identity
                     in 110 aa overlap) also P33645|CHPA_ECOLI pemk-like
                     protein 1 (mazf protein) from Escherichia coli (111 aa),
                     FASTA scores: opt: 104, E(): 0.18, (29.1% identity in 110
                     aa overlap). Also similar to Mycobacterium tuberculosis
                     Rv0659c (102 aa) (32.7% identity in 101 aa overlap);
                     Rv1102c (33.3% identity in 93 aa overlap) and Rv1495.
                     Protein product from Mb1977c detected using SWATH mass
                     spectrometry. Mb1977c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XZS9"
                     /db_xref="InterPro:IPR003477"
                     /db_xref="InterPro:IPR011067"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZS9"
BEGIN
        1 MTALPARGEV WWCEMAEIGR RPVVVLSRDA AIPRLRRALV APCTTTIRGL ASEVVLEPGS
       61 DPIPRRSAVN LDSVESVSVA VLVNRLGRLA DIRMRAICTA LEVAVDCSR
//