LOCUS       SIU00577.1               244 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            OXIDOREDUCTASE protein.
ACCESSION   LT708304-1990
PROTEIN_ID  SIU00577.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1974"
                     /note="Mb1974, -, len: 244 aa. Similar to Rv1939, len: 171
                     aa, from Mycobacterium tuberculosis strain H37Rv, (100.0%
                     identity in 167 aa overlap). Probable oxidoreductase (EC
                     1.-.-.-), similar to NP_302637.1|NC_002677 probable
                     oxidoreductase from Mycobacterium leprae (162 aa) Also
                     similar to NTAB_CHELE|P54990 nitrilotriacetate
                     monooxygenase component from Chelatobacter heintzii (322
                     aa), fasta scores: opt: 269, E(): 5.3e-11, (33.1% identity
                     in 151 aa overlap). And similar to Mycobacterium
                     tuberculosis probable monooxygenase components Rv0246,
                     Rv3567, and to a lesser extent, Rv3007c.
                     REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a
                     single base deletion (t-*) leads to a longer product with
                     a different COOH part compared to its homolog in
                     Mycobacterium tuberculosis H37Rv (244 aa versus 171 aa)."
                     /db_xref="GOA:A0A1R3Y070"
                     /db_xref="InterPro:IPR002563"
                     /db_xref="InterPro:IPR012349"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y070"
BEGIN
        1 MSCTFDMVPE TVDHLDEVGL RRVFGCFPCG VIAVCAMVDD QPVGMAASSF TSVSVDPPLV
       61 SICVQNCSTT WPKLRDRPRL GVSVLAEGHD AACMSLSRKE GNRFAGVFWS ELSSGGVVIA
      121 GAGAWLDCRP YAEIPAGDHL IALLEICAVR ADPETPPLVF HGSRFRRWSL DEDDRCAGTS
      181 CDHGDGGRSR RGPDRRPQWR WLSRLRRPGR DAAAGCLCGP AHLGLFARRA AGRRMRATAP
      241 AAHV
//