LOCUS SIU00577.1 244 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE OXIDOREDUCTASE protein. ACCESSION LT708304-1990 PROTEIN_ID SIU00577.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1974" /note="Mb1974, -, len: 244 aa. Similar to Rv1939, len: 171 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 167 aa overlap). Probable oxidoreductase (EC 1.-.-.-), similar to NP_302637.1|NC_002677 probable oxidoreductase from Mycobacterium leprae (162 aa) Also similar to NTAB_CHELE|P54990 nitrilotriacetate monooxygenase component from Chelatobacter heintzii (322 aa), fasta scores: opt: 269, E(): 5.3e-11, (33.1% identity in 151 aa overlap). And similar to Mycobacterium tuberculosis probable monooxygenase components Rv0246, Rv3567, and to a lesser extent, Rv3007c. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a single base deletion (t-*) leads to a longer product with a different COOH part compared to its homolog in Mycobacterium tuberculosis H37Rv (244 aa versus 171 aa)." /db_xref="GOA:A0A1R3Y070" /db_xref="InterPro:IPR002563" /db_xref="InterPro:IPR012349" /db_xref="UniProtKB/TrEMBL:A0A1R3Y070" BEGIN 1 MSCTFDMVPE TVDHLDEVGL RRVFGCFPCG VIAVCAMVDD QPVGMAASSF TSVSVDPPLV 61 SICVQNCSTT WPKLRDRPRL GVSVLAEGHD AACMSLSRKE GNRFAGVFWS ELSSGGVVIA 121 GAGAWLDCRP YAEIPAGDHL IALLEICAVR ADPETPPLVF HGSRFRRWSL DEDDRCAGTS 181 CDHGDGGRSR RGPDRRPQWR WLSRLRRPGR DAAAGCLCGP AHLGLFARRA AGRRMRATAP 241 AAHV //