LOCUS       SIU00572.1               409 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            ACYL-COA DEHYDROGENASE FADE17 protein.
ACCESSION   LT708304-1985
PROTEIN_ID  SIU00572.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="fadE17"
                     /locus_tag="BQ2027_MB1969C"
                     /note="Mb1969c, fadE17, len: 409 aa. Equivalent to
                     Rv1934c, len: 409 aa, from Mycobacterium tuberculosis
                     strain H37Rv, (100.0% identity in 409 aa overlap).
                     Probable fadE17, acyl-CoA dehydrogenase (EC 1.3.99.-),
                     highly similar to ACD_MYCLE|P46703 acyl-CoA dehydrogenase
                     from Mycobacterium leprae (389 aa), FASTA scores: opt:
                     414, E(): 2.6e-19, (28.3% identity in 407 aa overlap).
                     Also similar to many e.g. NP_249713.1|NC_002516 probable
                     acyl-CoA dehydrogenase from Pseudomonas aeruginosa (381
                     aa); NP_420614.1|NC_002696 acyl-CoA dehydrogenase family
                     protein from Caulobacter crescentus (355 aa);
                     CAB61610.1|AL133210 putative acyl-CoA dehydrogenase from
                     Streptomyces coelicolor (393 aa); etc. Also similar to
                     others from Mycobacterium tuberculosis e.g. fadE30 (385
                     aa); fadE31 (377 aa); C-terminus of fadE34 (711 aa); etc.
                     COULD BELONG TO THE ACYL-COA DEHYDROGENASES FAMILY."
                     /db_xref="GOA:A0A1R3XZU2"
                     /db_xref="InterPro:IPR006091"
                     /db_xref="InterPro:IPR009075"
                     /db_xref="InterPro:IPR009100"
                     /db_xref="InterPro:IPR013786"
                     /db_xref="InterPro:IPR036250"
                     /db_xref="InterPro:IPR037069"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZU2"
BEGIN
        1 MDVSYPPEAE AFRDRIREFV AEHLPPGWPG PGALPPHERE EFARHWRRAL AGAGLVAVSW
       61 PTEYGGGGLS PMEQVVLAEE FARAGAPERA ENDLLGIDLL GNTLIALGSE AQKRHFLPRI
      121 LSGEHRWCQG FSEPEAGSDL ASVRTRGVLD GDEWVINGHK IWTSAGTTAN WIFLLARTDP
      181 SAAKHRGLSF LLVPMDQPGV VVRPIVNAAG HSSFSEVFLT DARTSAGNVV GRVGDGWSTA
      241 MTLLGFERGS HIATAAIDFE RDLQRLCELA RDRGLHTDPR VRDGLAWCYA RVQIMRYRGY
      301 RDLTLALTGR PPGAEAAITK VIWSEYFRRY TDLAVEILGL EALGPRGPGN GGARLVPEAG
      361 TPNSPACWMD ELLYARAATI YAGSSQIQRN VIGERLLGLP KEPRPEVLC
//