LOCUS SIU00572.1 409 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE ACYL-COA DEHYDROGENASE FADE17 protein. ACCESSION LT708304-1985 PROTEIN_ID SIU00572.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="fadE17" /locus_tag="BQ2027_MB1969C" /note="Mb1969c, fadE17, len: 409 aa. Equivalent to Rv1934c, len: 409 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 409 aa overlap). Probable fadE17, acyl-CoA dehydrogenase (EC 1.3.99.-), highly similar to ACD_MYCLE|P46703 acyl-CoA dehydrogenase from Mycobacterium leprae (389 aa), FASTA scores: opt: 414, E(): 2.6e-19, (28.3% identity in 407 aa overlap). Also similar to many e.g. NP_249713.1|NC_002516 probable acyl-CoA dehydrogenase from Pseudomonas aeruginosa (381 aa); NP_420614.1|NC_002696 acyl-CoA dehydrogenase family protein from Caulobacter crescentus (355 aa); CAB61610.1|AL133210 putative acyl-CoA dehydrogenase from Streptomyces coelicolor (393 aa); etc. Also similar to others from Mycobacterium tuberculosis e.g. fadE30 (385 aa); fadE31 (377 aa); C-terminus of fadE34 (711 aa); etc. COULD BELONG TO THE ACYL-COA DEHYDROGENASES FAMILY." /db_xref="GOA:A0A1R3XZU2" /db_xref="InterPro:IPR006091" /db_xref="InterPro:IPR009075" /db_xref="InterPro:IPR009100" /db_xref="InterPro:IPR013786" /db_xref="InterPro:IPR036250" /db_xref="InterPro:IPR037069" /db_xref="UniProtKB/TrEMBL:A0A1R3XZU2" BEGIN 1 MDVSYPPEAE AFRDRIREFV AEHLPPGWPG PGALPPHERE EFARHWRRAL AGAGLVAVSW 61 PTEYGGGGLS PMEQVVLAEE FARAGAPERA ENDLLGIDLL GNTLIALGSE AQKRHFLPRI 121 LSGEHRWCQG FSEPEAGSDL ASVRTRGVLD GDEWVINGHK IWTSAGTTAN WIFLLARTDP 181 SAAKHRGLSF LLVPMDQPGV VVRPIVNAAG HSSFSEVFLT DARTSAGNVV GRVGDGWSTA 241 MTLLGFERGS HIATAAIDFE RDLQRLCELA RDRGLHTDPR VRDGLAWCYA RVQIMRYRGY 301 RDLTLALTGR PPGAEAAITK VIWSEYFRRY TDLAVEILGL EALGPRGPGN GGARLVPEAG 361 TPNSPACWMD ELLYARAATI YAGSSQIQRN VIGERLLGLP KEPRPEVLC //