LOCUS SIU00569.1 259 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN protein. ACCESSION LT708304-1982 PROTEIN_ID SIU00569.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1966C" /note="Mb1966c, -, len: 259 aa. Equivalent to Rv1931c, len: 259 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 259 aa overlap). Probable transcriptional regulatory protein. Similarity in C-terminal half to transcriptional activators e.g. Q43970 ARAC-LIKE PROTEIN (227 aa), FASTA scores: opt: 238, E(): 7.1e-07, (42.4% identity in 92 aa overlap). Similar to many probable transcription regulators in Streptomyces e.g. AL049587|SC5F2A.29 Streptomyces coelicolor (325 aa), FASTA scores: opt: 387, E(): 3.2e-16, (34.4% identity in 259 aa overlap). Mb1966c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XZS8" /db_xref="InterPro:IPR002818" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR018060" /db_xref="InterPro:IPR029062" /db_xref="UniProtKB/TrEMBL:A0A1R3XZS8" BEGIN 1 MVIVGFPGDP VDTVILPGGA GVDAARSEPA LIDWVKAVSG TARRVVTVCT GAFLAAEAGL 61 LGRTPSDDAL GLCRTFRPRI SGRSGRCRPD LHAQFAEGVD RGWSHRRHRP RAGTGRRRPR 121 HRDCPDGCPL ARPVSAPTRW ADPVRGSGVD ATRQTDLDPP GAGGHRGRAG GAHRIGELAQ 181 RAAMSPRHFT RVFSDEVGEA PGRYVERIRT EAARRQLEET HDTVVAIAAR CGFGTAETMR 241 RSFIRRVGIS PDQYRKAFA //