LOCUS       SIU00569.1               259 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            TRANSCRIPTIONAL REGULATORY PROTEIN protein.
ACCESSION   LT708304-1982
PROTEIN_ID  SIU00569.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1966C"
                     /note="Mb1966c, -, len: 259 aa. Equivalent to Rv1931c,
                     len: 259 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 259 aa overlap). Probable
                     transcriptional regulatory protein. Similarity in
                     C-terminal half to transcriptional activators e.g. Q43970
                     ARAC-LIKE PROTEIN (227 aa), FASTA scores: opt: 238, E():
                     7.1e-07, (42.4% identity in 92 aa overlap). Similar to
                     many probable transcription regulators in Streptomyces
                     e.g. AL049587|SC5F2A.29 Streptomyces coelicolor (325 aa),
                     FASTA scores: opt: 387, E(): 3.2e-16, (34.4% identity in
                     259 aa overlap). Mb1966c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XZS8"
                     /db_xref="InterPro:IPR002818"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR018060"
                     /db_xref="InterPro:IPR029062"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZS8"
BEGIN
        1 MVIVGFPGDP VDTVILPGGA GVDAARSEPA LIDWVKAVSG TARRVVTVCT GAFLAAEAGL
       61 LGRTPSDDAL GLCRTFRPRI SGRSGRCRPD LHAQFAEGVD RGWSHRRHRP RAGTGRRRPR
      121 HRDCPDGCPL ARPVSAPTRW ADPVRGSGVD ATRQTDLDPP GAGGHRGRAG GAHRIGELAQ
      181 RAAMSPRHFT RVFSDEVGEA PGRYVERIRT EAARRQLEET HDTVVAIAAR CGFGTAETMR
      241 RSFIRRVGIS PDQYRKAFA
//