LOCUS       SIU00542.1               143 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Anti-
            sigma B factor antagonist RsbV protein.
ACCESSION   LT708304-1955
PROTEIN_ID  SIU00542.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1939"
                     /note="Mb1939, -, len: 143 aa. Equivalent to Rv1904, len:
                     143 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.3% identity in 143 aa overlap). Conserved hypothetical
                     protein, some similarity to other hypothetical
                     Mycobacterium tuberculosis proteins e.g.
                     Rv2638|MTCY441.08|P71937 (148 aa), FASTA results: opt:
                     456, E(): 2.7e-23, (52.8% identity in 125 aa overlap);
                     Rv1365|Q11035 (128 aa), FASTA results: opt: 393, E():
                     1.4e-19, (48.8% identity in 123 aa overlap); and Rv3687c.
                     Also weak similarity to Q9WVX8|RSBV_STRCO ANTI-SIGMA B
                     FACTOR ANTAGONIST from Streptomyces coelicolor (113 aa).
                     Protein product from Mb1939 detected using SWATH mass
                     spectrometry. Mb1939 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XZQ1"
                     /db_xref="InterPro:IPR002645"
                     /db_xref="InterPro:IPR003658"
                     /db_xref="InterPro:IPR036513"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZQ1"
BEGIN
        1 MRTVAIGPGA GPSSTRPSSQ PSDLHSGLRA VTECTGSAVV VHVGGDIDAS NEVAWQRLVS
       61 KSAAIAIAPG PFVIDIRDLD FMGSCAYAVL AQESVRCRRR GVNMRLVSNQ PIVARTIAAC
      121 GLRRLIPLYA MVETALAPPP SAH
//