LOCUS SIU00539.1 430 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE CINA-LIKE PROTEIN CINA protein. ACCESSION LT708304-1952 PROTEIN_ID SIU00539.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="cinA" /locus_tag="BQ2027_MB1936" /note="Mb1936, cinA, len: 430 aa. Equivalent to Rv1901, len: 430 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 430 aa overlap). Probable cinA-like protein, strong similarity to competence damage proteins CinA of Bacillus subtilis and S. pneumoniae. FASTA results: Q55760 HYPOTHETICAL 44.7 KD PROTEIN (416 aa) opt: 755, E(): 0, (36.0% identity in 433 aa overlap). Protein product from Mb1936 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1936 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR001453" /db_xref="InterPro:IPR008135" /db_xref="InterPro:IPR008136" /db_xref="InterPro:IPR036425" /db_xref="InterPro:IPR036653" /db_xref="UniProtKB/Swiss-Prot:P63776" BEGIN 1 MAVSARAGIV ITGTEVLTGR VQDRNGPWIA DRLLELGVEL AHITICGDRP ADIEAQLRFM 61 AEQGVDLIVT SGGLGPTADD MTVEVVARYC GRELVLDDEL ENRIANILKK LMGRNPAIEP 121 ANFDSIRAAN RKQAMIPAGS QVIDPVGTAP GLVVPGRPAV MVLPGPPREL QPIWSKAIQT 181 APVQDAIAGR TTYRQETIRI FGLPESSLAD TLRDAEAAIP GFDLVEITTC LRRGEIEMVT 241 RFEPNAAQVY TQLARLLRDR HGHQVYSEDG ASVDELVAKL LTGRRIATAE SCTAGLLAAR 301 LTDRPGSSKY VAGAVVAYSN EAKAQLLGVD PALIEAHGAV SEPVAQAMAA GALQGFGADT 361 ATAITGIAGP SGGTPEKPVG TVCFTVLLDD GRTTTRTVRL PGNRSDIRER STTVAMHLLR 421 RTLSGIPGSP //