LOCUS       SIU00539.1               430 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CINA-LIKE PROTEIN CINA protein.
ACCESSION   LT708304-1952
PROTEIN_ID  SIU00539.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="cinA"
                     /locus_tag="BQ2027_MB1936"
                     /note="Mb1936, cinA, len: 430 aa. Equivalent to Rv1901,
                     len: 430 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 430 aa overlap). Probable cinA-like
                     protein, strong similarity to competence damage proteins
                     CinA of Bacillus subtilis and S. pneumoniae. FASTA
                     results: Q55760 HYPOTHETICAL 44.7 KD PROTEIN (416 aa) opt:
                     755, E(): 0, (36.0% identity in 433 aa overlap). Protein
                     product from Mb1936 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb1936 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="InterPro:IPR001453"
                     /db_xref="InterPro:IPR008135"
                     /db_xref="InterPro:IPR008136"
                     /db_xref="InterPro:IPR036425"
                     /db_xref="InterPro:IPR036653"
                     /db_xref="UniProtKB/Swiss-Prot:P63776"
BEGIN
        1 MAVSARAGIV ITGTEVLTGR VQDRNGPWIA DRLLELGVEL AHITICGDRP ADIEAQLRFM
       61 AEQGVDLIVT SGGLGPTADD MTVEVVARYC GRELVLDDEL ENRIANILKK LMGRNPAIEP
      121 ANFDSIRAAN RKQAMIPAGS QVIDPVGTAP GLVVPGRPAV MVLPGPPREL QPIWSKAIQT
      181 APVQDAIAGR TTYRQETIRI FGLPESSLAD TLRDAEAAIP GFDLVEITTC LRRGEIEMVT
      241 RFEPNAAQVY TQLARLLRDR HGHQVYSEDG ASVDELVAKL LTGRRIATAE SCTAGLLAAR
      301 LTDRPGSSKY VAGAVVAYSN EAKAQLLGVD PALIEAHGAV SEPVAQAMAA GALQGFGADT
      361 ATAITGIAGP SGGTPEKPVG TVCFTVLLDD GRTTTRTVRL PGNRSDIRER STTVAMHLLR
      421 RTLSGIPGSP
//