LOCUS       SIU00534.1               303 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 O-methyltransfera
            se protein.
ACCESSION   LT708304-1947
PROTEIN_ID  SIU00534.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1931C"
                     /note="Mb1931c, -, len: 303 aa. Equivalent to Rv1896c,
                     len: 303 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 303 aa overlap). Conserved
                     hypothetical protein. Similar to several (14) hypothetical
                     Mycobacterium tuberculosis proteins e.g. Rv0145|MTCI5.19
                     (317 aa), FASTA results: opt: 720, E(): 0, (41.6% identity
                     in 308 aa overlap); Q10552|YZ21_MYCTU (325 aa), opt: 689,
                     E(): 0, (40.5% identity in 304 aa overlap); Rv0726c,
                     Rv0731c, Rv3399, etc. and to related proteins in other
                     actinomycetes. Note that there is a substantial (134 bp)
                     overlap at the C-terminus with the C-terminus of the
                     downstream ORF, although both appear to be true coding
                     regions. Protein product from Mb1931c detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb1931c found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="GOA:Q7TZC0"
                     /db_xref="InterPro:IPR007213"
                     /db_xref="InterPro:IPR011610"
                     /db_xref="InterPro:IPR029063"
                     /db_xref="UniProtKB/Swiss-Prot:Q7TZC0"
BEGIN
        1 MTTPEYGSLR SDDDHWDIVS NVGYTALLVA GWRALHTTGP KPLVQDEYAK HFITASADPY
       61 LEGLLANPRT SEDGTAFPRL YGVQTRFFDD FFNCADEAGI RQAVIVAAGL DCRAYRLDWQ
      121 PGTTVFEIDV PKVLEFKARV LSERGAVPKA HRVAVPADLR TDWPTPLTAA GFDPQRPSAW
      181 SVEGLLPYLT GDAQYALFAR IDELCAPGSR VALGALGSRL DHEQLAALET AHPGVNMSGD
      241 VNFSALTYDD KTDPVEWLVE HGWAVDPVRS TLELQVGYGL TPPDVDVKID SFMRSQYITA
      301 VRA
//