LOCUS       SIU00531.1               376 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 putative
            oxidoreductase, nitronate monooxygenase family protein.
ACCESSION   LT708304-1944
PROTEIN_ID  SIU00531.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1927C"
                     /note="Mb1927c, -, len: 376 aa. Equivalent to Rv1894c,
                     len: 376 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 376 aa overlap). Conserved
                     hypothetical protein, weak similarity to some
                     oxidoreductases e.g. Q01284 2-NITROPROPANE DIOXYGENASE
                     PRECURSOR (378 aa), FASTA results: opt: 204, E(): 5.8e-06,
                     (34.3% identity in 140 aa overlap). Similar to
                     hypothetical Mycobacterium tuberculosis proteins e.g.
                     Rv3553|MTCY03C7.02c (355 aa), FASTA results: opt: 296,
                     E(): 1.6e-10, (32.9% identity in 167 aa overlap); Rv1533
                     (375 aa) (48.1% identity in 376 aa overlap); Rv0021c,
                     Rv2781c. Protein product from Mb1927c detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb1927c found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XZM5"
                     /db_xref="InterPro:IPR004136"
                     /db_xref="InterPro:IPR013785"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZM5"
BEGIN
        1 MHTAICDELG IEFPIFAFTH CRDVVVAVSK AGGFGVLGAV GFTPEQLEIE LNWIDEHIGD
       61 HPYGVDIVIP NKYEGMDSQL SADELAKTLR SMVPQEHLDF ARKILADHGV PVEDADEDSL
      121 QLLGWTEATA TPQVDAALKH PKMTMVANAL GTPPADMIKH IHDSGRKVAA LCGSPSQARK
      181 HADAGVDIII AQGGEAGGHC GEVGSIVLWP QVVKEVAPVP VLAAGGIGSG QQIAAALALG
      241 TQGAWTGSQW LMVEEAANTA VQQAAYVKAT SRDTVRSRSF TGKPARMLRN DWTEAWEQPE
      301 SPKPLGMPLQ YMVSGMAVKA THKYPNETVD VAFNPVGQVV GQFTKVEKTA TVIERWVQEY
      361 LEATARLDAL NAAASV
//