LOCUS SIU00531.1 376 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 putative oxidoreductase, nitronate monooxygenase family protein. ACCESSION LT708304-1944 PROTEIN_ID SIU00531.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1927C" /note="Mb1927c, -, len: 376 aa. Equivalent to Rv1894c, len: 376 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 376 aa overlap). Conserved hypothetical protein, weak similarity to some oxidoreductases e.g. Q01284 2-NITROPROPANE DIOXYGENASE PRECURSOR (378 aa), FASTA results: opt: 204, E(): 5.8e-06, (34.3% identity in 140 aa overlap). Similar to hypothetical Mycobacterium tuberculosis proteins e.g. Rv3553|MTCY03C7.02c (355 aa), FASTA results: opt: 296, E(): 1.6e-10, (32.9% identity in 167 aa overlap); Rv1533 (375 aa) (48.1% identity in 376 aa overlap); Rv0021c, Rv2781c. Protein product from Mb1927c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1927c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XZM5" /db_xref="InterPro:IPR004136" /db_xref="InterPro:IPR013785" /db_xref="UniProtKB/TrEMBL:A0A1R3XZM5" BEGIN 1 MHTAICDELG IEFPIFAFTH CRDVVVAVSK AGGFGVLGAV GFTPEQLEIE LNWIDEHIGD 61 HPYGVDIVIP NKYEGMDSQL SADELAKTLR SMVPQEHLDF ARKILADHGV PVEDADEDSL 121 QLLGWTEATA TPQVDAALKH PKMTMVANAL GTPPADMIKH IHDSGRKVAA LCGSPSQARK 181 HADAGVDIII AQGGEAGGHC GEVGSIVLWP QVVKEVAPVP VLAAGGIGSG QQIAAALALG 241 TQGAWTGSQW LMVEEAANTA VQQAAYVKAT SRDTVRSRSF TGKPARMLRN DWTEAWEQPE 301 SPKPLGMPLQ YMVSGMAVKA THKYPNETVD VAFNPVGQVV GQFTKVEKTA TVIERWVQEY 361 LEATARLDAL NAAASV //