LOCUS       SIU00503.1               699 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Phosphoenolpyruva
            te synthase (EC protein.
ACCESSION   LT708304-1916
PROTEIN_ID  SIU00503.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1899"
                     /EC_number="2.7.9.2"
                     /note="Mb1899, -, len: 699 aa. Equivalent to Rv1868, len:
                     699 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 699 aa overlap). Conserved
                     hypothetical protein, similar to products of three
                     consecutive ORFS in Mycobacterium leprae
                     MLCB2052.18|Z98604|B2052 (257 aa), FASTA scores: opt: 314,
                     E(): 9.9e-12, (35.2% identity in 213 aa overlap);
                     MLCB2052.17, and MLCB2052.16. Also similar to M.
                     tuberculosis hypothetical protein Rv2047c. Protein product
                     from Mb1899 detected using SWATH mass spectrometry. Mb1899
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZJ6"
BEGIN
        1 MQILVTDATG AVGRSVTRQL IAAGHTVSGI AQHPHDALDP RVDYVCASLR NPVLQELAGE
       61 ADAVIHLAPV DTSAPGGVGI TGLAHVANAA ARAGARLLFV SQAAGRPELY RQAETLVSTG
      121 WAPSLVIRIA PPVGRQLDWM VCRTVATLLR SKVSARPIRV LHLDDLVRFL VLALNTDRNG
      181 VVDLATPDTT NVVTAWRLLR SVDPHLRTRR VRSWEQLIPE VDIAAVQEDW NFEFGWQATE
      241 AIVDTGRGLV GRRLHPAGAT NGSGQLALPV EAPPRSVPSH GEPLGSAAPE GLEGEFDDRI
      301 DERFPVFSSA SLAEALPGPL TPMTLDVQLS GLRAAGRAMG RVLALGGVVA DEWERRAIAV
      361 FGHRPYIGVS ANIVAAAQLP GWDAQAVARR ALGEQPQVTE LLPFGRPQLA GGPLGSVAKV
      421 VVTARSLALL RHLRSDTHHY VAAADAEHLA AGQLASLPDA GLEVRIRLLR DRIHQGWILT
      481 VLWVIDTGVT AATLEHTRAG SAVSGGGMIM ESGRIGAEIA PLAAVLRADP PLCALANDGN
      541 LASIRALSAP AAAAVDAVIA RIGHRGLGEA ELANLTFADD PALLLKTAAE IAARPAGPAH
      601 PATLIQRLAA GTRSARELAH DTTIRFTHEL RMTLRELGSR RVAADVIDVV DDVFYLTCDE
      661 LITTPADARL RIKRRRAERE RLQAQRPPDV IDHAWVPVE
//