LOCUS SIU00497.1 346 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Probable alcohol dehydrogenase adhA protein. ACCESSION LT708304-1910 PROTEIN_ID SIU00497.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="adhA" /locus_tag="BQ2027_MB1893" /note="Mb1893, adhA, len: 346 aa. Equivalent to Rv1862, len: 346 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 346 aa overlap=. Probable adhA, alcohol dehydrogenase (EC 1.1.1.1), similar to ADH2_BACST|P42327 alcohol dehydrogenase (339 aa), FASTA scores: opt: 630, E(): 2.4e-32 (34.4% identity in 320 aa overlap). Contains PS00059 Zinc-containing alcohol dehydrogenases signature. Protein product from Mb1893 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1893 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XZX7" /db_xref="InterPro:IPR002328" /db_xref="InterPro:IPR011032" /db_xref="InterPro:IPR013154" /db_xref="InterPro:IPR014187" /db_xref="InterPro:IPR036291" /db_xref="UniProtKB/TrEMBL:A0A1R3XZX7" BEGIN 1 MVSPATTATM SAWQVRRPGP MDTGPLERVT TRVPRPAPSE LLVAVHACGV CRTDLHVTEG 61 DLPVHRERVI PGHEVVGEVI EVGSAVGAAA GGEFDRGDRV GIAWLRHTCG VCKYCRRGSE 121 NLCPQSRYTG WDADGGYAEF TTVPAAFAHH LPSGYSDSEL APLLCAGIIG YRSLLRTELP 181 PGGRLGLYGF GGSAHITAQV ALAQGAEIHV MTRGARARKL ALQLGAASAQ DAADRPPVPL 241 DAAILFAPVG DLVLPALEAL DRGGILAIAG IHLTDIPDLN YQQHLFQERQ IRSVTSNTRA 301 DARAFFDFAA QHHIEVTTPE YPLGQADRAL GDLSAGRIAG AAVLLI //