LOCUS SIU00492.1 261 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE MOLYBDATE-BINDING LIPOPROTEIN MODA protein. ACCESSION LT708304-1905 PROTEIN_ID SIU00492.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="modA" /locus_tag="BQ2027_MB1888" /note="Mb1888, modA, len: 261 aa. Equivalent to Rv1857, len: 261 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 261 aa overlap). Probable modA, molybdate-binding protein attached to membrane by lipid-modified N-terminal cysteine (contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site), component of molybdate transport system (see citation below). Shows strong similarity to precursors of periplasmic molybdate/sulphate binding proteins e.g. O31229|Y10817|ANY108174 ModA from Arthrobacter nicotinovorans (260 aa), FASTA score: opt: 725, E(): 0, (47.8% identity in 249 aa overlap). Mb1888 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P0A5Y1" /db_xref="InterPro:IPR005950" /db_xref="UniProtKB/Swiss-Prot:P0A5Y1" BEGIN 1 MRWIGLSTGL VSAMLVAGLV ACGSNSPASS PAGPTQGARS IVVFAAASLQ SAFTQIGEQF 61 KAGNPGVNVN FAFAGSSELA TQLTQGATAD VFASADTAQM DSVAKAGLLA GHPTNFATNT 121 MVIVAAAGNP KKIRSFADLT RPGLNVVVCQ PSVPCGSATR RIEDATGIHL NPVSEELSVT 181 DVLNKVITGQ ADAGLVYVSD ALSVATKVTC VRFPEAAGVV NVYAIAVLKR TSQPALARQF 241 VAMVTAAAGR RILDQSGFAK P //