LOCUS       SIU00492.1               261 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            MOLYBDATE-BINDING LIPOPROTEIN MODA protein.
ACCESSION   LT708304-1905
PROTEIN_ID  SIU00492.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="modA"
                     /locus_tag="BQ2027_MB1888"
                     /note="Mb1888, modA, len: 261 aa. Equivalent to Rv1857,
                     len: 261 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 261 aa overlap). Probable modA,
                     molybdate-binding protein attached to membrane by
                     lipid-modified N-terminal cysteine (contains PS00013
                     Prokaryotic membrane lipoprotein lipid attachment site),
                     component of molybdate transport system (see citation
                     below). Shows strong similarity to precursors of
                     periplasmic molybdate/sulphate binding proteins e.g.
                     O31229|Y10817|ANY108174 ModA from Arthrobacter
                     nicotinovorans (260 aa), FASTA score: opt: 725, E(): 0,
                     (47.8% identity in 249 aa overlap). Mb1888 found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:P0A5Y1"
                     /db_xref="InterPro:IPR005950"
                     /db_xref="UniProtKB/Swiss-Prot:P0A5Y1"
BEGIN
        1 MRWIGLSTGL VSAMLVAGLV ACGSNSPASS PAGPTQGARS IVVFAAASLQ SAFTQIGEQF
       61 KAGNPGVNVN FAFAGSSELA TQLTQGATAD VFASADTAQM DSVAKAGLLA GHPTNFATNT
      121 MVIVAAAGNP KKIRSFADLT RPGLNVVVCQ PSVPCGSATR RIEDATGIHL NPVSEELSVT
      181 DVLNKVITGQ ADAGLVYVSD ALSVATKVTC VRFPEAAGVV NVYAIAVLKR TSQPALARQF
      241 VAMVTAAAGR RILDQSGFAK P
//