LOCUS       SIU00475.1               466 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 pe-
            pgrs family protein pe_pgrs34 protein.
ACCESSION   LT708304-1888
PROTEIN_ID  SIU00475.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="PE_PGRS34"
                     /locus_tag="BQ2027_MB1871C"
                     /note="Mb1871c, PE_PGRS34, len: 466 aa. Similar to
                     Rv1840c, len: 515 aa, from Mycobacterium tuberculosis
                     strain H37Rv, (90.485% identity in 515 aa overlap). Member
                     of the Mycobacterium tuberculosis PE family, PGRS
                     subfamily of gly-rich proteins. Similar to many e.g.
                     Y03A_MYCTU|Q10637 hypothetical glycine-rich 49.6 kd
                     protein (603 aa), FASTA scores: opt: 1693, E(): 0, (53.1%
                     identity in 612 aa overlap); etc.
                     REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, an
                     in-frame deletion of 147 bp leads to a longer protein
                     compared to its homolog in Mycobacterium tuberculosis
                     strain H37Rv (466 aa versus 518 aa). Mb1871c found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="InterPro:IPR000084"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y0B4"
BEGIN
        1 MSFVVAAPEV VVAAASDLAG IGSAIGAANA AAAVPTMGVL AAGADEVSAA VADLFGAHAQ
       61 AYQALSAQAA LFHEQFVHAM TAGAGAYAGA EAADAAALDV LNGPFQALFG RPLIGDGANG
      121 APGQPGGPGG LLYGNGGNGG NGGIGQPGGA GGDAGLIGNG GNGGIGGPGA TGLAGGAGGL
      181 GKAGFAGGAG GTGGTGGLLY GNGGNGGNVP SGAADGGAGG DARLIGNGGD GGSVGAAPTG
      241 IGNGGNGGNG GWLYGDGGSG GSTLQGFSDG GTGGNAGMFG DGGNGGFSFF DGNGGDGGTG
      301 GTLIGNGGDG GNSVQTDGFL RGHGGDGGNA VGLIGNGGAG GAGSAGTGVF APGGGSGGNG
      361 GNGALLVGNG GAGGSGGPTQ IPSVAVPVTG AGGTGGNGGT AGLIGNGGNG GAAGVSGDGT
      421 PGTGGNGGYA QLIGDGGDGG PGDSGGPGGS GGTGGTLAGQ NGSPGG
//