LOCUS       SIU00470.1               628 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Predicted
            acyl esterases protein.
ACCESSION   LT708304-1883
PROTEIN_ID  SIU00470.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1866C"
                     /note="Mb1866c, -, len: 628 aa. Equivalent to Rv1835c,
                     len: 628 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 628 aa overlap). Conserved
                     hypothetical protein, some similarity to putative acylases
                     e.g. G216374 glutaryl 7-aca acylase precursor (634 aa)
                     FASTA scores, opt: 202, E(): 3.5e-06, (25.1% identity in
                     669 aa overlap). Also similar to Mycobacterium
                     tuberculosis hypothetical proteins Rv2800 and Rv1215c.
                     Protein product from Mb1866c detected using SWATH mass
                     spectrometry. Mb1866c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P0A5F6"
                     /db_xref="InterPro:IPR000383"
                     /db_xref="InterPro:IPR005674"
                     /db_xref="InterPro:IPR008979"
                     /db_xref="InterPro:IPR013736"
                     /db_xref="InterPro:IPR029058"
                     /db_xref="UniProtKB/Swiss-Prot:P0A5F6"
BEGIN
        1 MTRRGGSDAA WYSAPDQRSA YPRYRGMRYS SCYVTMRDGV RIAIDLYLPA GLTSAARLPA
       61 ILHQTRYYRS LQLRWPLRML LGGKPLQHIA ADKRRRRRFV ASGYAWVDVD VRGSGASFGA
      121 RVCEWSSDEI RDGAEIVDWI VRQPWCNGTV AALGNSYDGT SAELLLVNQH PAVRVIAPCF
      181 SLFDVYTDIA FPGGIHAAWF TDTWGRYNEA LDRNALHEVV GWWAKLPVTG MQPVQEDRDR
      241 SLRDGAIAAH RGNYDVHQIA GSLTFRDDVS ASDPYRGQPD ARLEPIGTPI ESGSINLISP
      301 HNYWRDVQAS GAAIYSYSGW FDGGYAHAAI KRFLTVSTPG SHLILGPWNH TGGWRVDPLR
      361 GLSRPDFDHD GELLRFIDHH VKGADTGIGS EPPVHYFTMV ENRWKSADTW PPPATTQSYY
      421 LSADRQLRPD APDCDSGADE YVVDQTAGTG ERSRWRSQVG IGGHVCYPDR KAQDAKLLTY
      481 TSAPLDHPLE VTGHVVVTLF ITSTSSDGTF FVYLEDVDPR GRVAYITEGQ LRAIHRRLSD
      541 GPPPYRQVVP YRTFASGDAW PLVPGEIARL TFDLLPTSYL FQPGHRIRIA IAGADASHFA
      601 ILPGCAPTVR VYRSRMHASR IDLPVIQP
//