LOCUS SIU00468.1 286 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Possible haloalkane dehalogenase protein. ACCESSION LT708304-1881 PROTEIN_ID SIU00468.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1864C" /note="Mb1864c, -, len: 286 aa. Equivalent to Rv1833c, len: 286 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 286 aa overlap). Possible haloalkane dehalogenase (EC 3.8.1.5). Similar to several haloalkane dehalogenase e.g. CAB45532.1|AJ243259 from Mycobacterium bovis (300 aa); also similar to LINB_PSEPA|P51698 1,3,4,6-tetrachloro-1,4-cyclohexadien from Pseudomonas paucimobilis (295 aa), FASTA scores: opt: 314, E(): 1.5e-13, (33.1% identity in 281 aa overlap). Protein product from Mb1864c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1864c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:P64304" /db_xref="InterPro:IPR000073" /db_xref="InterPro:IPR000639" /db_xref="InterPro:IPR023489" /db_xref="InterPro:IPR029058" /db_xref="UniProtKB/Swiss-Prot:P64304" BEGIN 1 MSIDFTPDPQ LYPFESRWFD SSRGRIHYVD EGTGPPILLC HGNPTWSFLY RDIIVALRDR 61 FRCVAPDYLG FGLSERPSGF GYQIDEHARV IGEFVDHLGL DRYLSMGQDW GGPISMAVAV 121 ERADRVRGVV LGNTWFWPAD TLAMKAFSRV MSSPPVQYAI LRRNFFVERL IPAGTEHRPS 181 SAVMAHYRAV QPNAAARRGV AEMPKQILAA RPLLARLARE VPATLGTKPT LLIWGMKDVA 241 FRPKTIIPRL SATFPDHVLV ELPNAKHFIQ EDAPDRIAAA IIERFG //