LOCUS SIU00460.1 292 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 UPF0749 protein Rv1825 protein. ACCESSION LT708304-1873 PROTEIN_ID SIU00460.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1856" /note="Mb1856, -, len: 292 aa. Equivalent to Rv1825, len: 292 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 292 aa overlap). Conserved hypothetical protein, weak similarity to Mycobacterium tuberculosis hypothetical proteins Q50610|MTCY1A11.20C|Rv1823|Z78020 (307 aa), FASTA scores: opt: 182, E(): 0.00044, (29.9% identity in 204 aa overlap); and Rv0012. Has a hydrophobic stretch, TMhelix from aa 67 to 85 Protein product from Mb1856 detected using SWATH mass spectrometry. Mb1856 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P64896" /db_xref="InterPro:IPR010273" /db_xref="UniProtKB/Swiss-Prot:P64896" BEGIN 1 MSENRPEPVA AETSAATTAR HSQADAGAHD AVRRGRHELP ADHPRSKVGP LRRTRLTEIL 61 RGGRSRLVFG TLAILLCLVL GVAIVTQVRQ TDSGDSLETA RPADLLVLLD SLRQREATLN 121 AEVIDLQNTL NALQASGNTD QAALESAQAR LAALSILVGA VGATGPGVMI TIDDPGPGVA 181 PEVMIDVINE LRAAGAEAIQ INDAHRSVRV GVDTWVVGVP GSLTVDTKVL SPPYSILAIG 241 DPPTLAAAMN IPGGAQDGVK RVGGRMVVQQ ADRVDVTALR QPKQHQYAQP VK //