LOCUS       SIU00460.1               292 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 UPF0749
            protein Rv1825 protein.
ACCESSION   LT708304-1873
PROTEIN_ID  SIU00460.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1856"
                     /note="Mb1856, -, len: 292 aa. Equivalent to Rv1825, len:
                     292 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 292 aa overlap). Conserved
                     hypothetical protein, weak similarity to Mycobacterium
                     tuberculosis hypothetical proteins
                     Q50610|MTCY1A11.20C|Rv1823|Z78020 (307 aa), FASTA scores:
                     opt: 182, E(): 0.00044, (29.9% identity in 204 aa
                     overlap); and Rv0012. Has a hydrophobic stretch, TMhelix
                     from aa 67 to 85 Protein product from Mb1856 detected
                     using SWATH mass spectrometry. Mb1856 found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:P64896"
                     /db_xref="InterPro:IPR010273"
                     /db_xref="UniProtKB/Swiss-Prot:P64896"
BEGIN
        1 MSENRPEPVA AETSAATTAR HSQADAGAHD AVRRGRHELP ADHPRSKVGP LRRTRLTEIL
       61 RGGRSRLVFG TLAILLCLVL GVAIVTQVRQ TDSGDSLETA RPADLLVLLD SLRQREATLN
      121 AEVIDLQNTL NALQASGNTD QAALESAQAR LAALSILVGA VGATGPGVMI TIDDPGPGVA
      181 PEVMIDVINE LRAAGAEAIQ INDAHRSVRV GVDTWVVGVP GSLTVDTKVL SPPYSILAIG
      241 DPPTLAAAMN IPGGAQDGVK RVGGRMVVQQ ADRVDVTALR QPKQHQYAQP VK
//